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Epigenetic Regulation of Filaggrin Gene Expression in Human Epidermal Keratinocytes

Lee J, Jang A, Seo SJ, Myung SC

BACKGROUND: Loss-of-function mutations in the filaggrin gene (FLG), which encodes an epidermal protein crucial for the formation of a functional skin barrier, have been identified as a major predisposing factor...
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Drug hypersensitivity reactions in Asia: regional issues and challenges

Thong BY, Lucas M, Kang HR, Chang YS, Li PH, Tang MM, Yun J, Fok JS, Kim BK, Nagao M, Rengganis , Tsai YG, Chung WH, Yamaguchi , Rerkpattanapipat T, Kamchaisatian W, Leung TF, Yoon HJ, Zhang L, Latiff AH, Fujisawa T, Thien F, Castells M, Demoly P, Wang JY, Pawankar R

There are geographical, regional, and ethnic differences in the phenotypes and endotypes of patients with drug hypersensitivity reactions (DHRs) in different parts of the world. In Asia, aspects of drug...
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Big Data-Driven Approach for Health Inequalities in Foreign Patients with Injuries Visiting Emergency Rooms

Kang JY, Kwon J, Sohn CH, Kim YJ, Lim HW, Lee SJ, Kim WY, Kim N, Seo DW

OBJECTIVES: Foreign patients are more likely to receive inappropriate health service in the emergency room. This study aimed to investigate whether there is health inequality between foreigners and natives who...
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Incidence of Febrile Neutropenia in Advanced Breast Cancer Patients Receiving Adjuvant Docetaxel-Doxorubicin-Cyclophosphamide Chemotherapy in Korea and Its Impact on Prognosis

Park BK, Gwak H, Lim ST, Suh YJ, Jeon YW

PURPOSE: The concurrent regimen of docetaxel, doxorubicin, and cyclophosphamide (TAC) has been categorized as a high-risk factor for febrile neutropenia (FN). The incidence of FN was reported to be as...
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The effect of Tamoxifen on Patients with Gynecomastia

Oh JM, Won TW

PURPOSE: Gynecomastia is the most common cause of male breast enlargement and is a disease which can occur in men of all ages. The purpose of this study was to...
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Schmorl's Nodes and Partial Lumbarization of S1 in European Human Remains of Korean War Casualty Excavated from the Arrowhead Ridge in DMZ

Jang YR, Kim MJ

The Ministry of National Defense of Agency for KIA Recovery and Identification (MAKRI) launched the Korean War casualty excavation project to retrieve war remains at the Arrowhead Ridge in the...
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Anatomical Characteristics of the Anterior Talofibular Ligament in Ankle Joint of Korean Population

Kwon HW, Park J, Kim D, Park KR, Lee MJ, Choi YJ, Kang H, Yoon KH, Cho J

The anterior talofibular ligament (ATFL) plays a role to stabilize ankle joint and prevent ankle sprain by limiting the motion range of ankle joint. The aim of this study was...
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Horizontal Facial Thirds of Young Adults in Two South-South Nigerian Ethnic Groups

EBOH DE

The study was undertaken to determine if there is a difference in length among the upper, middle and lower thirds of the face. Undergraduates, 18~30 years old, of Izon and...
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Reappraising the neurosurgical significance of the pterion location, morphology, and its relationship to optic canal and sphenoid ridge and neurosurgical implications

Kamath VG, Hande M

Frontolateral craniotomy procedures have advanced from conventional craniotomy to mini-craniotomy, and to contemporary keyhole surgery. In this context, it is important for the neurosurgeon to precisely locate the pterion. The...
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Does Nationality Matter for the Gunshot Brain Injury? Ten-Year Retrospective Observational Cadaveric Comparative Study for Gunshot TBI between Greece and Bulgaria

Nikova AS, Karakasi M, Pavlidis P, Birbilis T, Dimitrov I

OBJECTIVE: Penetrating brain trauma (PBT) caused by gunshot is one of the most lethal traumatic brain injuries (TBIs) and its management and confrontation is of great importance. METHODS: The authors searched...
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The Association between the Apolipoprotein E Gene Polymorphism and All-cause Mortality in the Korean Population

Choi CK, Kweon SS, Lee YH, Nam HS, Park KS, Ryu SY, Choi SW, Kim HY, Shin MH

BACKGROUND: Apolipoprotein E (APOE) gene polymorphism is associated with neurodegenerative and cardiovascular diseases. Although the effects of the gene differ by ethnic group, few studies have examined Asians. Therefore, the...
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Genetics of Hearing Loss in North Iran Population: An Update of Spectrum and Frequency of GJB2 Mutations

Koohiyan M, Azadegan-Dehkordi F, Koohian F, Hashemzadeh-Chaleshtori M

Diagnosis of pre-lingual hearing loss (HL) is difficult owing to the high number of genes responsible. The most frequent cause of HL is DFNB1 due to mutations in the GJB2...
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Normal Reference Plots for the Bioelectrical Impedance Vector in Healthy Korean Adults

Oh JH, Song S, Rhee H, Lee SH, Kim DY, Choe JC, Ahn J, Park JS, Shin MJ, Jeon YK, Lee HW, Choi JH, Lee HC, Cha KS

BACKGROUND: Accurate volume measurement is important in the management of patients with congestive heart failure or renal insufficiency. A bioimpedance analyser can estimate total body water in litres and has...
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A Rare Case of Lethal Prenatal-Onset Infantile Cortical Hyperostosis

Kim ST, Kim H, Kim HH, Lee NH, Han Y, Sung SI, Chang YS, Park WS

Infantile cortical hyperostosis, or Caffey's disease, usually presents with typical radiological features of soft tissue swelling and cortical thickening of the underlying bone. The disease can be fatal when it...
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Red Blood Cell Alloimmunization in Korean Patients With Myelodysplastic Syndrome and Liver Cirrhosis

Kim HY, Cho EJ, Chun S, Kim KH, Cho D

Red blood cell (RBC) alloimmunization varies across human populations and ethnic groups. We evaluated the characteristics of RBC alloimmunization and compared the risk of alloimmunization in Korean patients with myelodysplastic...
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Feasibility of Sub-Axial Cervical Laminar Screws, Including C7, in the Indian Population: A Study on 50 Patients Using Computed Tomography-Based Morphometry Measurements

Srivastava A, Nanda G, Mahajan R, Nanda A, Batra S, Mishra N, Pandita N, Chhabra HS

STUDY DESIGN: Observational study of computed tomography (CT) data. PURPOSE: We performed a CT-based radiographic analysis of sub-axial cervical lamina in the Indian population to assess the feasibility of laminar screws. OVERVIEW...
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Notified Incidence of Tuberculosis in Foreign-born Individuals in Jeju Province, Republic of Korea

Kim DS, Bae JM

OBJECTIVES: In the Republic of Korea (ROK), the notified incidence of tuberculosis in foreign-born individuals (NITFBI) has increased recently, as has the rate of multidrug-resistant (MDR) and rifampicin-resistant (RR) tuberculosis...
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Relationship between Health Behaviors and Marital Adjustment and Marital Intimacy in Multicultural Family Female Immigrants

Lee JY, Kim JS, Kim SS, Jeong JK, Yoon SJ, Kim SJ, Lee SM

BACKGROUND: This study analyzed the relationship between health behaviors and marital adjustment in multicultural couples to evaluate their health status. METHODS: Married couples (70 Korean men and their immigrant wives) completed...
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Comparison of food involvement scale (FIS) and use intention for block type sauce between US and Japanese consumers

Lee H, Kim SJ, Lee MA

PURPOSE: This study was conducted to compare the food involvement scale (FIS) of American and Japanese consumers. In addition, the effects of familiarity, likability, and expectations on willingness to use...
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Association of a genetic polymorphism of IL1RN with risk of acute pancreatitis in a Korean ethnic group

Park JW, Choi JS, Han KJ, Lee SH, Kim EJ, Cho JH

BACKGROUND/AIMS: Several epidemiological studies have validated the association of interleukin gene polymorphisms with acute pancreatitis (AP) in different populations. However, there have been few studies in Asian ethnic groups. We...
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