Korean J Med.
2010 Apr;78(4):512-517.
A case of radiation-induced sternal osteosarcoma after treatment of breast cancer
- Affiliations
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- 1Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea. dycho@kyuh.co.kr
- 2Department of Surgery, Konyang University College of Medicine, Daejeon, Korea.
- 3Department of Radiation Oncology, Konyang University College of Medicine, Daejeon, Korea.
- 4Department of Pathology, Konyang University College of Medicine, Daejeon, Korea.
Abstract
- Radiation-induced osteosarcoma is a very rare complication of radiation therapy, with a poor prognosis. We experienced a case of radiation-induced osteosarcoma of the sternum, in a patient who had had breast cancer treated with surgery, adjuvant chemotherapy, and adjuvant radiation therapy 6 years earlier. A 53-year-old woman complained of a painful anterior chest wall mass. The mass was diagnosed as osteosarcoma on biopsy. The radiation-induced osteosarcoma had an aggressive nature.