Korean J Med.  2010 Apr;78(4):512-517.

A case of radiation-induced sternal osteosarcoma after treatment of breast cancer

Affiliations
  • 1Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea. dycho@kyuh.co.kr
  • 2Department of Surgery, Konyang University College of Medicine, Daejeon, Korea.
  • 3Department of Radiation Oncology, Konyang University College of Medicine, Daejeon, Korea.
  • 4Department of Pathology, Konyang University College of Medicine, Daejeon, Korea.

Abstract

Radiation-induced osteosarcoma is a very rare complication of radiation therapy, with a poor prognosis. We experienced a case of radiation-induced osteosarcoma of the sternum, in a patient who had had breast cancer treated with surgery, adjuvant chemotherapy, and adjuvant radiation therapy 6 years earlier. A 53-year-old woman complained of a painful anterior chest wall mass. The mass was diagnosed as osteosarcoma on biopsy. The radiation-induced osteosarcoma had an aggressive nature.

Keyword

Osteosarcoma; Sternum; Radiation; Breast cancer

MeSH Terms

Biopsy
Breast
Breast Neoplasms
Chemotherapy, Adjuvant
Female
Humans
Middle Aged
Osteosarcoma
Prognosis
Sternum
Thoracic Wall
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