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FLASH Radiotherapy: A FLASHing Idea to Preserve Neurocognitive Function

Jo HJ, Oh T, Lee YR, Kang GS, Park HJ, Ahn GO

FLASH radiotherapy (FLASH RT) is a technique to deliver ultra-high dose rate in a fraction of a second. Evidence from experimental animal models suggest that FLASH RT spares various normal...
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The Efficiency of Radiation Shielding Sheet to Reduce Radiation Exposure during C-arm Fluoroscopy

Jeon H, Shin WC, Seol HY, Ki Y, Kim KB, Choo KS, Lee SD, Kang SW

Purpose: This study evaluates the radiation shielding performance of a new lead-free tungsten-based sheet to reduce the radiation exposure of operators and patients under C-arm fluoroscopy. Materials and Methods: A non-lead...
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Impact of Photon-Counting Detector Computed Tomography on Image Quality and Radiation Dose in Patients With Multiple Myeloma

Rau A, Neubauer J, Taleb L, Stein T, Schuermann T, Rau S, Faby S, Wenger S, Engelhardt M, Bamberg F, Weiss J

Objective: Computed tomography (CT) is an established method for the diagnosis, staging, and treatment of multiple myeloma. Here, we investigated the potential of photon-counting detector computed tomography (PCD-CT) in terms...
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Differential Perspectives by Specialty on Oligometastatic Colorectal Cancer: A Korean Oligometastasis Working Group’s Comparative Survey Study

Cho WK, Yoo GS, Rim CH, Jeong JU, Chie EK, Ahn YC, Cho HM, Um JW, Suh YG, Chang AR, Lee JH, On behalf of the Oligometastasis Working Group, Korean Cancer Association

Purpose Despite numerous studies on the optimal treatments for oligometastatic disease (OMD), there is no established interdisciplinary consensus on its diagnosis or classification. This survey-based study aimed to analyze the...
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Comparison of sequential versus concurrent chemoradiation regimens in non-metastatic muscle-invasive bladder cancer

Vieira HM, Kasper DP, Wang R, Smith LM, Enke CA, Bergan RC, Teply BA, Baine MJ

Purpose: The treatment approach for non-metastatic bladder cancer is guided by an invasion of the muscular layer of the bladder wall. Radical cystectomy is the recommended treatment for muscle-invasive disease....
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Radiation exposure during different percutaneous renal puncture techniques: A YAU endourology & urolithiasis study

Sener TE, Tanidir Y, Ketenci S, Kutukoglu U, Dorucu D, Cayir H, Pietropaolo A, Emiliani E, Somani B

Purpose: Radiation exposure is affected by C-arm fluoroscopy device positioning during percutaneous renal puncture. Our aim was to compare the exposure of surgeon's lens, hand and chest with a fluoroscopy...
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A pilot study of half-value layer measurements using a semiconductor dosimeter for intraoral radiography

Nouchi S, Yoshida H, Miki Y, Tezuka Y, Ogawa R, Ogura I

Purpose: This pilot study was conducted to evaluate half-value layer (HVL) measurements obtained using a semi conductor dosimeter for intraoral radiography. Materials and Methods: This study included 8 aluminum plates, 4...
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Reparative, Neuroprotective and Anti-neurodegenerative Effects of Granulocyte Colony Stimulating Factor in Radiation-Induced Brain Injury Model

Gürkan G, Atasoy Ö, Çini N, Sever İH, Özkul B, Yaprak G, Şirin C, Uyanıkgil Y, Kızmazoğlu C, Erdoğan MA, Erbaş O

Objective : This animal model aimed to compare the rat group that received brain irradiation and did not receive additional treatment (only saline) and the rat group that underwent brain...
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Effect of Bevacizumab Treatment in Cerebral Radiation Necrosis : Investigation of Response Predictors in a Single-Center Experience

Lee SH, Choi JW, Kong DS, Seol HJ, Nam DH, Lee JI

Objective : Bevacizumab is a feasible option for treating cerebral radiation necrosis (RN). We investigated the clinical outcome of RN after treatment with bevacizumab and factors related to the initial...
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Oncologic Outcomes of T1–T2N0 Glottic Cancer Treatment: Single Center Experiences of 417 Patients Over 20 Years

Choi SY, Chung MK, Ahn YC, Oh D, Son YI

Background and Objectives For T1–T2 early glottic cancer, single modality treatment with radiation therapy (RT) or transoral laser microsurgery is the standard therapeutic option. However, the choice between surgery and...
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Mesenchymal Stem Cell-Derived Exosomes are Effective for Radiation Enteritis and Essential for the Proliferation and Differentiation of Lgr5+ Intestinal Epithelial Stem Cells by Regulating Mir-195/Akt/b-Catenin Pathway

Yang L, Fang C, Song C, Zhang Y, Zhang R, Zhou S

BACKGROUND: Radiation enteritis (RE) is a common complication of abdominal or pelvic radiotherapy, which when severe, could be life-threatening. Currently, there are no effective treatments. Studies have shown that mesenchymal...
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Reduction of Radiation Dose to Eye Lens in Cerebral 3D Rotational Angiography Using Head Off-Centering by Table Height Adjustment: A Prospective Study

Ryu JC, Yoon JT, Kim BJ, Kim MH, Moon EJ, Suh PS, Roh YH, Moon HH, Kwon B, Lee DH, Song Y

Objective: Three-dimensional rotational angiography (3D-RA) is increasingly used for the evaluation of intracranial aneurysms (IAs); however, radiation exposure to the lens is a concern. We investigated the effect of head...
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Nuclear Factor Erythroid 2-Related Factor 2/Kelch-Like ECH-Associated Protein 1 as a Predictor of Prognosis and Radiotherapy Resistance in Patients With Locally Advanced Rectal Cancer: A Prospective Analysis

Park JM, Kim S, Bae SU, Byun SJ, Seo I, Lee HW

Background: The nuclear factor erythroid 2-related factor 2/Kelch-like ECH-associated protein 1 (Nrf2/Keap1) signaling pathway is involved in the regulation of cellular responses to oxidative stress. Nrf2 acts as a cell...
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One-Week versus Two-Week Chemoradiotherapy Followed by Curative Surgery in Rectal Cancer: Long-Term Comparative Pooled Analysis of Two Prospective Multicenter Phase II Trials

Sung SY, Kim DY, Jang HS, Kim TH, Park HC, Chie EK, Nam TK, Kim SH, Lee JH

Purpose The optimal short-course chemotherapeutic regimen for rectal cancer has not been clearly defined until now. KROG 10-01 and KROG 11-02 prospective trials investigated the efficacy and safety of 1-...
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Efficacy of Prophylactic Cranial Irradiation According to the Risk of Extracranial Recurrence in Limited-Stage Small Cell Lung Cancer

Lee TH, Chung JH, Wu HG, Kim S, Lee JH, Keam B, Kim JS, Kim KH, Kim BH, Kim HJ

Purpose We aimed to evaluate the effectiveness of prophylactic cranial irradiation (PCI) for “early brain metastasis”, which occurs before extracranial recurrence (ECR), and “late brain metastasis”, which occurs after ECR,...
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Evaluation of the role of inflammatory blood markers in predicting the pathological response after neoadjuvant chemoradiation in patients with locally advanced rectal cancer

Manoochehry S, Rasouli HR, Ahmadpour F, Keramati A

Purpose: This study aimed to evaluate the role of inflammatory blood markers in predicting the pathological response rate after neoadjuvant chemoradiation (neo-CRT) in patients with locally advanced rectal cancer (LARC). Materials...
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Research progress and treatment of radiation enteritis and gut microbiota

Ren H, Wu Q, Sun Z, Fang M, Liu J, Luo J

Radiation enteritis is a kind of intestinal radiation injury in patients with pelvic and retroperitoneal malignancies after radiotherapy, and its occurrence and development process are very complicated. At present, studies...
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Radiation-induced change after Gamma Knife radiosurgery for cerebral arteriovenous malformations

Lee HS, Kim HY, Lee Si, Woo JB, Jin SC, Kim MS

Objective: Radiation-induced change (RIC) on magnetic resonance imaging after Gamma Knife radiosurgery (GKRS) for cerebral arteriovenous malformations (AVMs) is not rare. We reviewed patients who underwent GKRS for AVMs and...
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Nationwide changes in radiation oncology travel and location of care before and during the COVID-19 pandemic

De Leo AN, Giap F, Culbert MM, Drescher N, Brisson RJ, Cassidy V, Augustin EM, Casper A, Horowitz DH, Cheng SK, Yu JB

Purpose: Patients with cancer are particularly vulnerable to coronavirus disease (COVID). Transportation barriers made travel to obtain medical care more difficult during the pandemic. Whether these factors led to...
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Radiology Residents’ Independent Diagnosis of Appendicitis Using 2-mSv Computed Tomography: A Secondary Analysis of a Large Pragmatic Randomized Trial

Cho J, Kim HY, Lee S, Park JH, Lee KH

Objective: To compare the diagnostic performance and clinical outcomes of 2-mSv computed tomography (CT) and conventional-dose CT (CDCT), following radiology residents’ interpretation of CT examinations for suspected appendicitis. Materials and Methods:...
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