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Dioscin Decreases Breast Cancer Stem-like Cell Proliferation via Cell Cycle Arrest by Modulating p38 Mitogen-activated Protein Kinase and AKT/mTOR Signaling Pathways

Chae WO, Kim GD

Dioscin (DS), a steroidal saponin, has been shown to have anti-cancer activity by exerting antioxidant effects and inducing apoptosis. However, the anti-cancer activity of DS in breast cancer-derived stem cells...
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The Effect of Self-Acupressure on Peripheral Neuropathy, Disturbance in Daily Activity, and Quality of Life in Breast Cancer Patients undergoing Chemotherapy

Kim SY, Park JS

Purpose This study was done to investigate the effects of self-acupressure on chemotherapy-induced peripheral neuropathy (CIPN), the degree of disturbance in daily activity, and the quality of life in breast cancer...
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The relationship between lymphedema severity and awareness of lymphedema surgery

Lee HS, Bae YC, Nam SB, Yi CR, Yoon JA, Kim JH

Background During the early stages of lymphedema, active physiologic surgical treatment can be applied. However, lymphedema patients often have limited knowledge and misconceptions regarding lymphedema and surgical treatment. We analyzed...
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Drawing Test Form for Depression: The Development of Drawing Tests for Predicting Depression Among Breast Cancer Patients

Kim J, Chung S

Objective The aim of this study is to develop a drawing test form and it’s scoring system for measuring depressive symptoms of breast cancer patients. Methods We enrolled 95 breast cancer...
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Clinical Exercise Prescription for Cardiovascular Health in Breast Cancer Survivors

Lee Kya

Conventional treatments accessible to breast cancer survivors after diagnosis include cancer therapies with cardiotoxic effects such as trastuzumab and/or anthracycline-based chemotherapy, which can result in undesirable cardiac injuries known as...
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Docetaxel-loaded PLGA nanoparticles to increase pharmacological sensitivity in MDA-MB-231 and MCF-7 breast cancer cells

Tran P, Nguyen TN, Lee Y, Tran PN, Park JS

This study aimed to develop docetaxel (DTX) loaded poly(lactic-coglycolic acid) (PLGA) nanoparticles (DTX-NPs) and to evaluate the different pharmacological sensitivity of NPs to MCF-7 and MDA-MB-231 breast cancer cells. NPs...
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Accuracy of Digital Breast Tomosynthesis for Detecting Breast Cancer in the Diagnostic Setting: A Systematic Review and Meta-Analysis

Ko MJ, Park DA, Kim SH, Ko ES, Shin KH, Lim W, Kwak BS, Chang JM

Objective: To compare the accuracy for detecting breast cancer in the diagnostic setting between the use of digital breast tomosynthesis (DBT), defined as DBT alone or combined DBT and digital...
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Deep Learning-Based Artificial Intelligence for Mammography

Yoon JH, Kim EK

During the past decade, researchers have investigated the use of computer-aided mammography interpretation. With the application of deep learning technology, artificial intelligence (AI)-based algorithms for mammography have shown promising results...
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Assessment of Additional MRI-Detected Breast Lesions Using the Quantitative Analysis of ContrastEnhanced Ultrasound Scans and Its Comparability with Dynamic Contrast-Enhanced MRI Findings of the Breast

Lee SY, Woo OH, Shin HS, Song SE, Cho KR, Seo BK, Hwang SY

Purpose To assess the diagnostic performance of contrast-enhanced ultrasound (CEUS) for additional MR-detected enhancing lesions and to determine whether or not kinetic pattern results comparable to dynamic contrast-enhanced magnetic resonance...
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Changes in Korean National Healthcare Insurance Policy and Breast Cancer Surgery Trend in Korea

Rayzah M, Ryu JM, Lee JH, Nam SJ, Kim SW, Lee SK, Yu J, Lee KT, Bang SI, Mun GH, Pyon JK, Jeon BJ, Lee JE

Background: Since April 2015, the Korean National Health Insurance (NHI) has reimbursed breast cancer patients, approximately 50% of the cost of the breast reconstruction (BR) procedure. We aimed to investigate...
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Dynamic Contrast Enhanced MRI and Intravoxel Incoherent Motion to Identify Molecular Subtypes of Breast Cancer with Different Vascular Normalization Gene Expression

Tsai WC, Chang KM, Kao KJ

Objective: To assess the expression of vascular normalization genes in different molecular subtypes of breast cancer and to determine whether molecular subtypes with a higher vascular normalization gene expression can...
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Feasibility of Extracorporeal Shock Wave Therapy for Complex Upper Limb Morbidity in Breast Cancer Patient

Ha MC, Shin JC, Jung YS, Im SH

Upper limb morbidity including shoulder pain, lymphedema, adhesive capsulitis, myofascial pain syndrome, and limited range of motions (LROMs) occurs frequently in breast cancer patients. Especially restricted upper limb motion aggravated...
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Programmed Death Ligand 1 Immunohistochemistry in TripleNegative Breast Cancer: Evaluation of Inter-Pathologist Concordance and Inter-Assay Variability

Purpose: The programmed death ligand 1 (PD-L1) SP142 assay with a 1% immune cell (IC) cutoff is approved for the selection of advanced triple-negative breast cancer (TNBC) patients for atezolizumab...
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Detection of Contralateral Breast Cancer Using Diffusion-Weighted Magnetic Resonance Imaging in Women with Newly Diagnosed Breast Cancer: Comparison with Combined Mammography and Whole-Breast Ultrasound

Ha SM, Chang JM, Lee SH, Kim ES, Kim SY, Kim YS, Cho N, Moon WK

Objective: To compare the screening performance of diffusion-weighted (DW) MRI and combined mammography and ultrasound (US) in detecting clinically occult contralateral breast cancer in women with newly diagnosed breast cancer. Materials...
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Herpes Zoster in Breast Cancer Patients: A 15-Year Experience from a Single Tertiary Referral Center in Korea

Song S, Lim JW, Baek J, Roh JY, Park HK, Kim HJ

  • KMID: 2516141
  • Korean J Dermatol.
  • 2021 May;59(4):284-289.
Background: Breast cancer is the second most common cancer and the most common cause of cancer deaths in Korean women. Although tumor-induced mediators and cancer therapy can suppress cell-mediated immunity,...
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Multiple Primary Malignant Neoplasms: A Case Report of Breast Mucinous Carcinoma and Extramammary Diffuse Large B-Cell Lymphoma in a Male Patient

Kim SY, Lee JY

Multiple primary malignant neoplasms refer to two or more malignancies in an individual that are not related. We report a case of a 78-year-old male with concurrent breast mucinous carcinoma...
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Patient-specific surgical options for breast cancer-related lymphedema: technical tips

Kwon JG, Hong DW, Suh HP, Pak CJ, Hong JP

In order to provide a physiological solution for patients with breast cancer-related lymphedema (BCRL), the surgeon must understand where and how the pathology of lymphedema occurred. Based on each patient’s...
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Subjective and Objective Assessment of Monoenergetic and Polyenergetic Images Acquired by Dual-Energy CT in Breast Cancer

Wang X, Liu D, Jiang S, Zeng X, Li L, Yu T, Zhang J

Objective: To objectively and subjectively assess and compare the characteristics of monoenergetic images [MEI (+)] and polyenergetic images (PEI) acquired by dual-energy CT (DECT) of patients with breast cancer. Materials and...
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Heregulin-β1 Activates NF-E2-related Factor 2 and Induces Manganese Superoxide Dismutase Expression in Human Breast Cancer Cells via Protein Kinase B and Extracellular Signal-regulated Protein Kinase Signaling Pathways

Park JY, Saeidi S, Kim EH, Kim DH, Na HK, Keum JS, Surh YJ

Heregulin-β1, a ligand of ErbB-2 and ErbB-3/4 receptors, has been reported to potentiate oncogenicity and metastatic potential of breast cancer cells. In the present work, treatment of human mammary cancer...
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Understanding the Mechanistic Link between Bisphenol A and Cancer Stem Cells: A Cancer Prevention Perspective

Winz C, Suh N

Endocrine disruptors, such as bisphenol A (BPA), have become more frequently present in the environment as contaminants, especially in industrialized countries. Long-term effects of these environmental contaminants in humans are...
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