Korean J Med.  2010 Sep;79(3):295-300.

A case of angiomyolipoma of the liver

Affiliations
  • 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. ceciliak@yuhs.ac
  • 2Department of Radiology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Angiomyolipoma occurs most commonly in the kidneys; the liver is the second most frequent site of involvement. Hepatic angiomyolipoma is a rare, benign, mesenchymal neoplasm, composed mainly of blood vessels, smooth muscle cells, fat, and myelocomponents. Radiologic findings are non-specific because the various elements of these neoplasms vary in their proportion and distribution within the tumor. Thus, data obtained by imaging technologies such as computed tomography, ultrasonography, or magnetic resonance imaging tend to be merely suggestive; definitive diagnosis usually requires histologic confirmation. We report here a case of angiomyolipoma in an incidental tumor of the liver of a 53-year-old female. Tissue was removed from the tumor by ultrasonography-guided gun biopsy and subjected to immunohistochemical analysis. Data showed that tumor cells were positive for HMB-45 and SMA, but negative for cytokeratin, anti-hepatocyte antigen, and alpha-fetoprotein. The patient did not receive any treatment and is being followed up.

Keyword

Angiomyolipoma; Liver

MeSH Terms

alpha-Fetoproteins
Angiomyolipoma
Biopsy
Blood Vessels
Female
Humans
Keratins
Liver
Magnetic Resonance Imaging
Middle Aged
Myocytes, Smooth Muscle
Keratins
alpha-Fetoproteins
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