Korean J Med.  2007 Oct;73(4):432-437.

Cerebral salt wasting following pituitary surgery for macroadenoma

Affiliations
  • 1Department of Internal Medicine, College of Medicine, Dankook University, Cheonan, Korea. hjinkim@dankook.ac.kr
  • 2Department of Neurosurgery, College of Medicine, Dankook University, Cheonan, Korea.

Abstract

The central nervous system (CNS) has important roles in the regulation of sodium and water homeostasis, so the risk of hyponatremia is increased for patients with neurological disorders. Cerebral salt wasting (CSW) is a syndrome that is characterized by hyponatremia and extracellular volume contraction, and these problems are caused by natriuresis and the concomitant polyuria in patient with intracranial disease. It is critical to differentiate CSW from syndrome of inappropriate secretion of antidiuretic hormone (SIADH) for patients with hyponatremia and after they experience cerebral insults. This is because fluid restriction is the treatment of choice for SIADH and administration of isotonic or hypertonic saline is important for treating CSW. We report here on a case of CSW following trassphenoidal surgery for pituitary tumor in a 67-year-old man with nonfunctioning pituitary macroadenoma. Hyposmotic hyponatremia, increased urine output and signs of dehydration developed postoperatively, and the patient was managed by water and salt supplementation.

Keyword

Hyponatremia; Cerebral salt wasting; Syndrome of inappropriate secretion of antidiuretic hormone; Pituitary adenoma

MeSH Terms

Aged
Central Nervous System
Dehydration
Homeostasis
Humans
Hyponatremia
Inappropriate ADH Syndrome
Natriuresis
Nervous System Diseases
Pituitary Neoplasms
Polyuria
Sodium
Sodium
Full Text Links
  • KJM
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr