Korean J Med.  2007 Dec;73(6):666-669.

Typhlitis due to propylthiouracil in a patient with hyperthyroidism

• Ryu SY
• Jang YY
• Kim SY
• Park KG
• Kim HS

Abstract

Typhlitis is one of the most ominous complications in immunocompromised patients. Neutropenic enterocolitis or typhlitis is a clinical syndrome characterized by fever, diarrhea and abdominal pain that occurs in neutropenic patients. It has been reported as a complication of childhood leukemia, but is now known to occur in adults with solid malignancies, acquired immunodeficiency syndrome (AIDS) or bone marrow transplantation (BMT). The association of typhlitis and propylthiouracil has not been previously reported. We report a case of a 42-year-old female patient with typhlitis due to propylthiouracil patient with hyperthyroidism.

Keyword

Typhlitis; Propylthiouracil; Hyperthyroidism

MeSH Terms

Abdominal Pain
Acquired Immunodeficiency Syndrome
Adult
Bone Marrow Transplantation
Diarrhea
Enterocolitis, Neutropenic
Female
Fever
Humans
Hyperthyroidism*
Immunocompromised Host
Leukemia
Propylthiouracil*
Typhlitis*
Propylthiouracil