Korean J Med.  2003 Nov;65(Suppl 3):S792-S797.

A case of concomitant hyperthyroidism and hyperparathyroidism due to parathyroid hyperplasia

Affiliations
  • 1Department of Internal Medicine, Eulji University School of Medicine, Daejeon, Korea. lskendo@hanmail.net
  • 2Department of General Surgery, Eulji University School of Medicine, Daejeon, Korea.
  • 3Department of Pathology, Eulji University School of Medicine, Daejeon, Korea.

Abstract

Concurrent hyperthyroidism and primary hyperparathyroidism in the same patient is rare. In most cases of concomitant hyperthyroidism and primary hyperparathyroidism, serum calcium levels are quite elevated. However, recently we diagnosed a patient who had hyperthyroidism [Triiodothyroxine 6.81 nmol/L (1.23-3.39), Free thyroxine 92.88 pmol/L (10.32-25.80), TSH 0.05 mU/L (0.2-7.0)] and primary hyperparathyroidism [parathyroid hormone 163 pg/mL (12-72)] with mild hypercalcemia 2.78 mmol/L (2.03-2.60)]. We treated this patient with propylthiouracil and pamidronate and normalized her thyroid function and serum calcium levels. We then performed subtotal thyroidectomy and removed two parathyroid glands and clipped one parathyroid gland using a hemoclip. The pathologic diagnosis was confirmed to be Graves' disease and parathyroid hyperplasia. The patient was healthy, and serum levels of PTH, calcium and phosphorus were normal after the operation.

Keyword

Hyperthyroidism; Hyperparathyroidism; Parathyroid hyperplasia

MeSH Terms

Calcium
Diagnosis
Graves Disease
Humans
Hypercalcemia
Hyperparathyroidism*
Hyperparathyroidism, Primary
Hyperplasia*
Hyperthyroidism*
Parathyroid Glands
Phosphorus
Propylthiouracil
Thyroid Gland
Thyroidectomy
Thyroxine
Calcium
Phosphorus
Propylthiouracil
Thyroxine
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