Soonchunhyang Med Sci.  2014 Dec;20(2):103-107. 10.0000/sms.2014.20.2.103.

Incidental Findings with Technetium-99m Methoxyisobutrlisonitrile Imaging of Ectopic Parathyroid Hyperplasia in Patient with Intrathyroidal Parathyroid Hyperplasia

Affiliations
  • 1Department of Internal Medicine, Soonchunhyang University Hospital, Cheonan, Korea. 285874@hanmail.net
  • 2Department of Nuclear Medicine, Soonchunhyang University Hospital, Cheonan, Korea.

Abstract

We report a case of intrathyroidal and ectopic parathyroid hyperplasia in a 47-year-old female patient with secondary hyperparathyroidism. During evaluation for end stage renal disease, hypercalcemia and hyperparathyroidism were detected in laboratory exam and thyroid nodules were found in computed tomography, and thyroid ultrasonography. In subsequent dual-phase technetium-99m methoxyisobutrlisonitrile (Tc-99m MIBI) scan, delayed focal uptakes were found in thyroid gland and the upper mediastinum. I-123 scan showed photon defects in thyroid gland and no uptake in the upper mediastinum. The imaging findings indicate intrathyroidal and mediastinal ectopic parathyroid hyperplasia. The intrathyroidal and ectopic parathyroid hyperplasia were confirmed by surgical approach. Tc-99m MIBI scan was useful for detecting ectopic parathyroid hyperplasia concomitant intrathyroidal parathyroid lesion.

Keyword

Parathyroid neoplasms; Technetium Tc 99m sestamibi; Hyperparathyroidism

MeSH Terms

Female
Humans
Hypercalcemia
Hyperparathyroidism
Hyperparathyroidism, Secondary
Hyperplasia*
Incidental Findings*
Kidney Failure, Chronic
Mediastinum
Middle Aged
Parathyroid Neoplasms
Technetium Tc 99m Sestamibi
Thyroid Gland
Thyroid Nodule
Ultrasonography
Technetium Tc 99m Sestamibi
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