Korean J Blood Transfus.  1996 Dec;7(2):257-261.

A case of autoimmune hemolytic anemia due to autoanti-Ce

Abstract

A 12-year-old female with histiocytosis X accompanied by autoimmune hemolytic anemia. During the episode of hemolysis, the hemoglobin level fell to 5.2 g/dL. The direct antiglobulin test was weakly positive. The anti-C and anti-e were identified in her serum. The Rh subgroup of her family(father, mother and brother) including the patient, were all same as DCe. The antibodies which showed anti-C and anti-e specificity were confirmed autoanti-Ce(non-separable) using the serum absorbed with various known Rh phenotyped RBCs. Two packed RBCs phenotyped as DeE were transfused for correction of anemia. Acute and delayed hemolytic transfusion reactions were not noted after transfusion. Identification of blood group specific autoantibodies may be benificial in such case for blood transfusion.


MeSH Terms

Anemia
Anemia, Hemolytic, Autoimmune*
Antibodies
Autoantibodies
Blood Group Incompatibility
Blood Transfusion
Child
Coombs Test
Female
Hemolysis
Histiocytosis, Langerhans-Cell
Humans
Mothers
Sensitivity and Specificity
Antibodies
Autoantibodies
Full Text Links
  • KJBT
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr