Clin Psychopharmacol Neurosci.  2018 Nov;16(4):501-504. 10.9758/cpn.2018.16.4.501.

Quetiapine Induced Autoimmune Hemolytic Anemia in a Child Patient: A Case Report

• Arici A
• Altun H
• Acipayam C

• KMID: 2428981
• DOI: http://doi.org/10.9758/cpn.2018.16.4.501

Abstract

Autoimmune hemolytic anemia is a disease characterized with destruction of erythrocytes as a result of antibody produce against patient's own erythrocytes and anemia. Autoimmune hemolytic anemia can be roughly stratified into two groups according to serological features and secondary causes including drugs induced hemolytic anemia. Drugs induced autoimmune hemolytic anemia is very rare in pediatric patients. Even though hematological side effects such as leucopenia, agranulocytosis, eosinophilia, thrombocytopenic purpura and aplastic anemia might occur due to psychotropic drug use; to the best of our knowledge there is no autoimmune hemolytic anemia case due to quetiapine, an atypical antipsychotics, in literature. We hereby describe the first child case of autoimmune hemolytic anemia during quetiapine treatment.We also are pointing out that one should keep in mind serious hematological side effects with atypical antipsychotic drug use with this case report.

Keyword

Autoimmune hemolytic anemia; Antipsychotic agents; Quetiapine fumarate; Child; Hematological side effects

MeSH Terms

Agranulocytosis
Anemia
Anemia, Aplastic
Anemia, Hemolytic
Anemia, Hemolytic, Autoimmune*
Antipsychotic Agents
Child*
Eosinophilia
Erythrocytes
Humans
Purpura, Thrombocytopenic
Quetiapine Fumarate*
Antipsychotic Agents
Quetiapine Fumarate