Korean J Med.  2003 Nov;65(Suppl 3):S912-S916.

A case of eosinophilic cholecystitis with hepatitis associated with clonorchiasis

• Kim ES
• Ryu ST
• Lee MH
• Wi HS
• Kim IH
• Ahn SI
• Kim CS

Abstract

Eosinophilic cholecystitis is a rare condition of cholecystitis which was first described by the Albot in 1949. We describe a case of eosinophilic cholecystitis associated with Clonorchis sinensis. A 42-year-old woman presented with a classic history of acute cholecystitis and a peripheral eosinophilia of 56% without an allergic history. An abdominal CT scan showed thickened, edematous gallbladder wall but no cholelithiasis, and an cholecystectomy was performed. Pathological examination revealed diffuse infiltration of eosinophils throughout all gallbladder wall layers and marked eosinophilic infiltration of the liver. Skin test for clonorchis sinensis was strong positive and serologic test for Clonorchis sinensis antibody was high titer. The serum alkaline phosphatase, SGOT, SGPT and eosinophil count normalized within a week after praziquantel medication.

Keyword

Eosinophilia; Cholecystitis; Clonorchis sinensis

MeSH Terms

Adult
Alanine Transaminase
Alkaline Phosphatase
Aspartate Aminotransferases
Cholecystectomy
Cholecystitis*
Cholecystitis, Acute
Cholelithiasis
Clonorchiasis*
Clonorchis sinensis
Eosinophilia
Eosinophils*
Female
Gallbladder
Hepatitis*
Humans
Liver
Praziquantel
Serologic Tests
Skin Tests
Tomography, X-Ray Computed
Alanine Transaminase
Alkaline Phosphatase
Aspartate Aminotransferases
Praziquantel