Korean J Infect Dis.
2000 Oct;32(5):380-387.
Antibiotic Sensitivity to the Causative Organism of Acute Simple
Urinary Tract Infection for Recent 3 Years
Abstract
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BACKGROUND: We studied the antibiotic sensitivities to the causative microorganisms of acute
simple urinary tract infection for recent 3 years.
METHODS
We analyzed 112 microorganisms and their antibiotic sensitivities of the 104 patients
who were admitted to or visited the Department of Urology, Catholic University St. Marys
Hospital and had more than 10cfu/mL on urine culture from June 1996 to January 1999
retrospectively.
RESULTS
The chance of gram negative and positive as causative microorganisms was 72.3% and
27.7% respectively. The most common pathogenic microorganisms were Escherichia coli (67.0%)
followed by a-hemolytic streptococci, Entercoccus. In gram negative acute UTI, imipenem,
sulperanzone showed relatively higher sensitivity, while cotrimoxazole, ampicillin showed
relatively lower sensitivity. In gram positive, vancomycin, penicillin showed relatively
higher sensitivity, while ampicillin, imipenem showed relatively lower sensitivity.
CONCLUSIONS
We consider that gram negative microorganisms, especially E. coli, is the main
cause of acute simple UTI. But, we should be concerned about the increase of gram positive
organisms and other gram negative organisms besides E. coli. Regarding to the choice of
adequate drug in the treatment of UTI, it is necessary to consider the change of pathologic
microorganisms.