Korean J Infect Dis.  2001 Aug;33(4):305-309.

Lethal Measles Pneumonia after Allogenic Hematopoietic Stem Cell Transplantation

• Paik CN
• Lee DG
• Jung HW
• Choi JH
• Cho YK
• Park HJ
• Lee SH
• Park YH
• Lee KY
• Shin WS
• Min WS
• Kim CC

Abstract

As a result of the enlarging pool of unvaccinated children and young adults, there has been an increase in measles in our countries. In these situation, it has been reported that measles associated pneumoinia is easily complicated with fatal respiratory failure, especially in immunocompromised patients. Herein we report the case of lethal measles pneumonia after allogenic hematopoietic stem cell transplantation in adults proven by autopsy. Recently, one case of measles was encountered in a 39-year-old female patients after allogenic bone marrow transplanted case (chronic myelogenous leukemia), who progressed into interstitial pneumonia pattern, despite treatment including antibiotics, immunoglobulin. The patient died of giant cell pneumonia compatible with that of measles which was comfirmed in the section of necropsy lung specimen.

Keyword

Pneumonia; Measles; Bone marrow transplantation

MeSH Terms

Adult
Anti-Bacterial Agents
Autopsy
Bone Marrow
Bone Marrow Transplantation
Child
Female
Giant Cells
Hematopoietic Stem Cell Transplantation*
Hematopoietic Stem Cells*
Humans
Immunocompromised Host
Immunoglobulins
Lung
Lung Diseases, Interstitial
Measles*
Pneumonia*
Respiratory Insufficiency
Young Adult
Anti-Bacterial Agents
Immunoglobulins