Korean J Dermatol.  2008 Oct;46(10):1445-1448.

A Case of Dystrophic Calcinosis Cutis Secondary to Localized Scleroderma

• Park HY
• Kim JH
• Ahn SK
• Choi EH

Abstract

Localized scleroderma is a connective tissue disorder that's characterized by thickening and fibrosis of the skin due to excessive collagen deposition. Localized scleroderma differs from systemic sclerosis according to the absence of Raynaud's phenomenon, sclerodactyly or systemic involvement. Dystrophic calcinosis cutis occurs in up to 10% of the patients with systemic sclerosis, but it is rare in localized scleroderma. Only seven cases of localized scleroderma with calcinosis cutis have been reported in the English medical literature. We report here on a 57-year-old woman with localized scleroderma with dystrophic calcification, and this was identified by the histopathology and CT scans. The serologic tests for the autoimmune antibodies anti-RNP, ENA and anti-SS-A(Ro) were all positive.

Keyword

Anti-RNP antibody; Dystrophic calcinosis cutis; Localized scleroderma

MeSH Terms

Antibodies
Calcinosis
Collagen
Connective Tissue
Female
Fibrosis
Humans
Middle Aged
Scleroderma, Localized
Scleroderma, Systemic
Serologic Tests
Skin
Antibodies
Collagen