Korean J Dermatol.  2011 Nov;49(11):1038-1040.

Purple Glove Syndrome Caused by Intravenous Phenytoin Injection

• Shin WU
• Song HJ

Abstract

Purple glove syndrome (PGS) is a rare complication of intravenous phenytoin use that is poorly understood and potentially serious. The characteristic features of PGS are pain, edema, and discoloration at the injection site that spreads to the distal limbs. Diagnosis of PGS can be made from clinical presentation, and treatment is usually restricted to conservative therapy. A 7-year-old girl was treated with phenytoin for epilepsy and was referred to our department for violaceous color change and edema on intravenous injection site of the left hand. It was consistent with PGS, and to our knowledge, it is first report in Korea.

Keyword

Phenytoin; Purple glove syndrome

MeSH Terms

Child
Edema
Epilepsy
Extremities
Hand
Humans
Injections, Intravenous
Korea
Phenytoin
Phenytoin