J Korean Epilepsy Soc.  2009 Jun;13(1):31-34.

Parkinsonism Caused by Phenytoin Intoxication-A Case Report

Affiliations
  • 1Department of Neurology, Gachon University Gil Hospital, Incheon, Korea. djshin@gilhospital.com

Abstract

Parkinsonism is a very rare complication of phenytoin. The authors experienced a 71-year-old man who presented progressive cognitive decline, postural tremor, bradykinesia and gait disturbance. Laboratory test and brain imaging revealed no abnormality that commonly causes parkinsonism. The only abnormal finding was elevation of serum phenytoin above the therapeutic level. The patient showed marked improvement of symptoms by reduction of phenytoin dosage. Here we report a case of phenytoin induced parkinsonism.

Keyword

Phenytoin; Parkinsonism; Toxicity

MeSH Terms

Aged
Gait
Humans
Hypokinesia
Neuroimaging
Parkinsonian Disorders
Phenytoin
Tremor
Phenytoin
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