J Korean Epilepsy Soc.
2009 Jun;13(1):31-34.
Parkinsonism Caused by Phenytoin Intoxication-A Case Report
- Affiliations
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- 1Department of Neurology, Gachon University Gil Hospital, Incheon, Korea. djshin@gilhospital.com
Abstract
- Parkinsonism is a very rare complication of phenytoin. The authors experienced a 71-year-old man who presented progressive cognitive decline, postural tremor, bradykinesia and gait disturbance. Laboratory test and brain imaging revealed no abnormality that commonly causes parkinsonism. The only abnormal finding was elevation of serum phenytoin above the therapeutic level. The patient showed marked improvement of symptoms by reduction of phenytoin dosage. Here we report a case of phenytoin induced parkinsonism.