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Severity of Daytime Sleepiness and Parkinsonian-Like Symptoms in Korean Adults Aged 50–64 Years

Shin C, Kim REY, Thomas RJ, Yun CH, Lee SK, Abbott RD

Background and Purpose While excessive daytime sleepiness can predate Parkinson’s disease in late-life, its association with parkinsonian-like (P-L) symptoms in middle age are unknown. Since neurodegeneration can appear decades before...
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Dystonia Responsive to Dopamine: POLG Mutations Should Be Considered If Sensory Neuropathy Is Present

Qiu J, Kumar KR, Watson E, Ahmad K, Sue CM, Hayes MW

The POLG gene encodes mitochondrial DNA polymerase, and mutations in this gene cause a spectrum of disorders related to mitochondrial DNA depletion or deletion. Dystonia has only rarely been reported...
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Manganese and Movement Disorders: A Review

Kulshreshtha D, Ganguly J, Jog M

Scientific and technological advances achieved with industrial expansion have led to an ever-increasing demand for heavy metals. This demand has, in turn, led to increased contamination of soil, water and...
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Juvenile Parkinsonism with PARK2 Gene Mutation Misdiagnosed as Dopa-responsive Dystonia: a Case Report

Hong S, Lee S, Cho SR

Parkinson's disease is prevalent in elderly patients, usually aged over 50 years. If clinical symptoms of parkinsonism appear before 21 years of age, it is called juvenile parkinsonism (JP). JP...
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Association between Olfactory Deficit and Motor and Cognitive Function in Parkinson’s Disease

Yoo HS, Chung SJ, Lee YH, Ye BS, Sohn YH, Lee PH

Objective To investigate whether baseline olfactory dysfunction in Parkinson’s disease (PD) patients is associated with baseline and longitudinal motor and cognitive function. Methods We recruited 228 drug-naïve PD patients who were...
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Early Impairment of Chopsticks Skills in Parkinsonism Suggests Progressive Supranuclear Palsy

Kim YE, Ma Hi, Seong GH, Huh JY, Park J, Song J, An S, Kim YJ

Background and Purpose Chopsticks are a primary eating utensil in East Asia, but systematic assessments of chopsticks skills in parkinsonian disorders is lacking. We aimed to identify any differences in chopsticks...
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Oro-Pharyngeal Dysphagia in Parkinson's Disease and Related Movement Disorders

Kwon M, Lee JH

Oro-pharyngeal dysphagia is a common symptom in patients with Parkinson's disease (PD) and related disorders, even in their early stage of diseases. Dysphagia in these patients has been underdiagnosed, probably...
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Urodynamic Mechanisms Underlying Overactive Bladder Symptoms in Patients With Parkinson Disease

Vurture G, Peyronnet , Palma JA, Sussman RD, Malacarne , Feigin A, Palmerola , Rosenblum , Frucht S, Kaufmann H, Nitti VW, Brucker BM

PURPOSE: To assess the urodynamic findings in patients with Parkinson disease (PD) with overactive bladder symptoms. METHODS: We performed a retrospective chart review of all PD patients who were seen in...
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Spatiotemporal Gait Parameter Comparison for Parkinson's Disease, Multiple System Atrophy, and Other Parkinsonism Diseases

Bae CH, Jeong HW, Yun JY, Lee JE, Han SJ

The aim of this study was to compare and quantify the spatiotemporal and gait parameters obtained by foot pressure analysis during the gait in a group of Parkinson's disease (PD)...
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Trends in the Prevalence of Drug-Induced Parkinsonism in Korea

Byun JH, Cho H, Kim YJ, Kim JS, Baik JS, Jang S, Ma HI

PURPOSE: Discontinuation of offending drugs can prevent drug-induced parkinsonism (DIP) before it occurs and reverse or cure it afterwards. The aim of this study was to investigate the prevalence of...
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Reduced Uptake on Dopamine Transporter Imaging by Methylphenidate

Ha J, Ko J, Song JT, Hong JY

No abstract available.
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Pseudobulbar Affect in Parkinsonian Disorders: A Review

Hakimi M, Maurer CW

Pseudobulbar affect (PBA) is a neurological symptom of inappropriate and uncontrollable laughter or crying that occurs secondary to a variety of neurological conditions, including parkinsonian disorders. PBA is a socially...
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Abnormal Eye Movements in Parkinsonism and Movement Disorders

Jung I, Kim JS

Abnormal eye movements are commonly observed in movement disorders. Ocular motility examination should include bedside evaluation and laboratory recording of ocular misalignment, involuntary eye movements, including nystagmus and saccadic intrusions/oscillations,...
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A Patient with Myotonic Dystrophy Type 1 Presenting as Parkinsonism

Choi JH, Lee JY, Kim HJ, Jeon B

The current body of literature contains 5 reports of myotonic dystrophy (DM) with parkinsonism: 4 reports of DM type 2 and 1 report of clinically suspected DM type 1. To...
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Tau Positron Emission Tomography Imaging in Degenerative Parkinsonisms

Lyoo CH, Cho H, Choi JY, Ryu YH, Lee MS

In recent years, several radiotracers that selectively bind to pathological tau proteins have been developed. Evidence is emerging that binding patterns of in vivo tau positron emission tomography (PET) studies...
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Femur Fractures in Parkinsonism: Analysis of a National Sample Cohort in South Korea

An SJ, Lee SH, Lee SY, Kwon JW, Lee SJ, Kim YJ

BACKGROUND AND PURPOSE: Falling with a femur fracture is a serious event that negatively affects the quality of life of elderly individuals as well as patients with parkinsonism. This study...
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Apraxia: Review and Update

Park JE

Praxis, the ability to perform skilled or learned movements is essential for daily living. Inability to perform such praxis movements is defined as apraxia. Apraxia can be further classified into...
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‘Hummingbird’ Sign in a Patient with Guam Parkinsonism-Dementia Complex

Yeo T, Tan LC

We present a case of a 71-year-old male Chamorro patient from Guam who presented with progressive supranuclear palsy (PSP)-Richardson’s syndrome. Considering his strong family history of parkinsonism and a PSP...
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Dementia and Parkinsonism-a Rare Presentation of Intracranial Dural Arteriovenous Fistulae

Gopinath M, Nagesh C, Santhosh K, Jayadevan

Intracranial dural arteriovenous fistulae (DAVF) are acquired fistulous communications between dural arterial branches and dural venous sinuses or cortical veins with the nidus located within the leaflets of the duramater....
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Family Functioning and Communication in Spouses of Patients with Parkinsonism

Kang SY, Yang MH, Lee JA, Jang W, Lee CS, Kim YS

BACKGROUND: Patients with parkinsonism exhibit motor symptoms, cognitive impairment, and neuropsychiatric changes, and these symptoms increase caregiver burden. Family dynamics can be influenced by the presence of comorbidities, which is...
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