Korean J Anesthesiol.  1996 Oct;31(4):513-518. 10.4097/kjae.1996.31.4.513.

Effect of Preoperative Infiltration on Postoperative Analgesic Requirements in Total Abdominal Hysterectomy Patients

• Kim DH
• Park CH
• Lee SC

• KMID: 2240365
• DOI: http://doi.org/10.4097/kjae.1996.31.4.513

Abstract

BACKGROUND: The concept of preemptive analgesia has been suggested recently as another technique in the treatment of postoperative pain. This study was undertaken to determine whether preoperative blockade of nociceptive input with operative bupivacaine would exert a preemptive effect on postoperative analgesia.
METHODS
40 patients undergoing hysterectomy with general anesthesia were allocated randomly to receive either 0.25% bupivacaine 40ml infiltrated into the proposed wound line 10min before incision or no infiltration. Patient-controlled analgesia fentanyl and ketorolac were administered to both groups during first 48 postoperative hours.
RESULTS
Pain scores and cumulative fentanyl and ketorolac consumption dosage at 12, 24, 36, 48 hours after surgery was similar in both groups.
CONCLUSIONS
We concluded that preincisional infiltration with bupivacaine had no advantage in reducing postoperative analgesic requirements or pain scores after hysterectomy.

Keyword

Analgesia pain; patient-controlled; postoperative; preemptive; Anesthetic techniques general; regional; infiltration; Anesthetics; local bupivacaine; Pain measurement; postoperative

MeSH Terms

Analgesia
Analgesia, Patient-Controlled
Anesthesia, General
Anesthetics
Bupivacaine
Fentanyl
Humans
Hysterectomy*
Ketorolac
Pain Measurement
Pain, Postoperative
Wounds and Injuries
Anesthetics
Bupivacaine
Fentanyl
Ketorolac