Korean J Anesthesiol.  1994 Jan;27(1):54-59. 10.4097/kjae.1994.27.1.54.

The Effect of Transdermal Scopolamine Patch on Nausea and Vomiting after Epidural Injection of Morphine

• Lee HJ
• Moon DE
• Suh JH
• Kim SN

• KMID: 2239235
• DOI: http://doi.org/10.4097/kjae.1994.27.1.54

Abstract

Sixty patients, undergoing major gynecologic surgery with lumbar epidural anesthesia, were randomly selected 32 patients to apply a transdermal scopolamine patch (Kimite MyoungMoon, Korea) on the skin behind one ear. We were divided into 2 groups. Control group; epidural morphine 4mg were given and not applied scopolamine patch. Experimental group; epidural morphine 4mg were given and applied transdermal scopolamine patch on the skin behind her ear at the night before surgery. They were followed up for 3 days postoperatively and statistical analysis was done. There was a significant (p<0.05) reduction in nausea and vomiting between experimental group and control group. There was no significant incresed incidence in scopolamine side effects. However, despite receiving transderrnal scopolamine patch there was still a high incidence (43.8%) of nausea and vomiting.

Keyword

Epidural morphine; Transdermal scopolamine; Nausea; Vomiting

MeSH Terms

Anesthesia, Epidural
Ear
Female
Gynecologic Surgical Procedures
Humans
Incidence
Injections, Epidural*
Morphine*
Nausea*
Scopolamine Hydrobromide*
Skin
Vomiting*
Morphine
Scopolamine Hydrobromide