Korean J Anesthesiol.  2004 Mar;46(3):306-310. 10.4097/kjae.2004.46.3.306.

Comparison of Postoperative Nausea and Vomiting between Gynecologic Surgery and Cesarean-Section during Intravenous Patient-Controlled Analgesia with Fentanyl

• Park CK
• Choi HY
• Oh IY
• Cho CK
• Kim MS

• KMID: 2236696
• DOI: http://doi.org/10.4097/kjae.2004.46.3.306

Abstract

BACKGROUND
The purpose of this study was to compare the incidence of postoperative nausea and vomiting (PONV) in patients undergoing major gynecologic surgery with those undergoing Cesarean-section during intravenous patient-controlled analgesia (PCA).
METHODS
Seventy two patients received general anesthesia with enflurane. Group 1 patients underwent major gynecologic surgery, and group 2 patients were parturients who underwent Cesarean-section. Postoperatively, fentanyl was continuously infused i.v. using Accufuser PLUS (basal, 2 ml/h; bolus, 0.5 ml; lockout interval, 15 min) containing fentanyl 25microgram/kg in saline. PONV was evaluated at 6, 12, 24 and 36 h after starting continuous infusion and compared in the two groups.
RESULTS
The incidence of PONV was significantly lower in group 2 (14%) than in group 1 (67%) (P < 5).
CONCLUSIONS
Our results show that the incidence of PONV was lower for Cesarean-section than for gynecologic surgery.

Keyword

cesarean-section; fentanyl; gynecologic surgery; patient-controlled analgesia; postoperative nausea and vomiting (PONV)

MeSH Terms

Analgesia, Patient-Controlled*
Anesthesia, General
Enflurane
Female
Fentanyl*
Gynecologic Surgical Procedures*
Humans
Incidence
Postoperative Nausea and Vomiting*
Enflurane
Fentanyl