Infect Chemother.  2008 Apr;40(2):121-126. 10.3947/ic.2008.40.2.121.

A Case of Perianal Abscess due to Panton-Valentine Leukocidin Positive Community-Associated Methicillin-Resistant Staphylococcus aureus : Report in Korea and Literature Review from the Far East

• Park C
• Lee DG
• Choi SM
• Park SH
• Choi JH
• Yoo JH
• Hur JA
• Shin WS

• KMID: 2230016
• DOI: http://doi.org/10.3947/ic.2008.40.2.121

Abstract

Community-associated methicillin resistant Staphylococcus aureus (CA-MRSA) with Panton-Valentine leukocidin (PVL) genes have recently emerged worldwide, but infections due to PVL carrying CA-MRSA strains have never been reported in Korea. We report a case of extensive perianal abscess due to PVL+ CA-MRSA in a 76-year-old Korean female patient, of which genetic background was very close to USA300. It belonged to staphylococcal cassette chromosome mec element (SCCmec) type IV, ST8 of multilocus sequence typing (MLST), type 1 spa type, and accessory gene regulator locus (agr) group I. Comprehensive literature reviews from the Far East showed molecular characteristics were diverse and PVL genes were infrequently found than in western countries.

Keyword

Abscess; Panton-Valentine Leukocidin; Community-associated Infection; Staphylococcus aureus; Methicillin resistance

MeSH Terms

Abscess
Aged
Bacterial Toxins
Exotoxins
Far East
Female
Humans
Korea
Leukocidins
Lifting
Methicillin Resistance
Methicillin-Resistant Staphylococcus aureus
Multilocus Sequence Typing
Staphylococcus aureus
Bacterial Toxins
Exotoxins
Leukocidins

Figure

• 

  Figure 1 Pelvic CT scan revealed bilateral thickening of levator ani muscle around anus extending to the bilateral ischiorectal fascia (arrow), especially on right side, with focal nodular infiltration. Thickening of skin and soft tissue due to inflammation was also observed in the medial aspect of buttock.

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