Korean J Clin Microbiol.  2008 Oct;11(2):129-131. 10.5145/KJCM.2008.11.2.129.

A Fatal Case of Infective Endocarditis Caused by Community-Associated Methicillin-Resistant Staphylococcus aureus ST72 in Korea

Affiliations
  • 1Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea. drjwchung@cau.ac.kr

Abstract

The advent of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has been a worldwide threat to public health for the past decade. We report a fatal case of infective endocarditis caused by a non-USA300, Panton-Valentine leukocidin toxin-negative CA-MRSA clone. This is a serious case of CA-MRSA infection caused by a sequence type (ST) 72 clone, which is one of the common CA-MRSA clones circulating in Korea where serious CA-MRSA infections have been rare.

Keyword

Staphylococcus aureus; Endocarditis; Methicillin Resistant

MeSH Terms

Bacterial Toxins
Clone Cells
Endocarditis
Exotoxins
Korea
Leukocidins
Methicillin Resistance
Methicillin-Resistant Staphylococcus aureus
Public Health
Staphylococcus aureus
Bacterial Toxins
Exotoxins
Leukocidins

Figure

  • Fig. 1. Molecular detection of type IV SCCmec and PVL virulence gene. PCR amplification with specific primers shows the presence of mecA and type IV SCCmec in the CA-MRSA isolate. However, PCR for detection of the PVL gene shows the absence of PVL gene in the isolate.


Reference

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