Korean J Clin Microbiol.
2005 Apr;8(1):66-73.
Antimicrobial Resistance of Clinically Important Bacteria Isolated from 12 Hospitals in Korea in 2004
- Affiliations
-
- 1Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea. leekcp@yumc.yonsei.ac.kr
- 2Department of Laboratory Medicine, Pochon cha University College of Medicine, Sungnam, Korea.
- 3Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.
- 4Department of Laboratory Medicine, Kosin University College of Medicine, Busan, Korea.
- 5Department of Laboratory Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.
- 6Department of Laboratory Medicine, Hanyang University College of Medicine, Seoul, Korea.
- 7Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
- 8Department of Laboratory Medicine, Chonnam National Univeristy Medical School, Gwangju, Korea.
- 9Department of Laboratory Medicine, Ajou University College of Medicine, Suwon, Korea.
- 10Department of Laboratory Medicine, Keonyang University Medical College, Daejeon, Korea.
- 11Department of Laboratory Medicine, Sooncheonhyang University College of Medicine, Gumi, Korea.
- 12Department of Laboratory Medicine, Cheju Hanmaeum Hospital, Cheju, Korea.
- 13Food Microbiology Division, Center for Food Safety Evaluation, Korea Food and Drug Administration, Seoul, Korea.
Abstract
- BACKGROUND
A rapid increase in antimicrobial-resistant bacteria has become a serious problem in many countries including Korea, but the rate and pattern of antimicrobial resistance may vary significantly depending on countries and even on hospitals. The aim of this study was to determine the nationwide prevalence of resistance among frequently isolated bacterial pathogens in Korea.
METHODS
Routine susceptibility data for medically important bacterial pathogens from 12 university hospital and general hospital laboratories in Korea were analysed by patient group. These pathogens had been isolated during the period from April to November in 2004.
RESULTS
The proportion of methicillin-resistant Staphylococcus aureus (MRSA) was 67%. Van-comycin-resistance rate of Enterococcus faecalis was 1% and that of E.faecium was 20%. The resistance rates of Streptococcus pneumoniae to penicillin and Haemophilus influenzae to ampicillin were 70% and 54%, respectively. The resistant rates of Escherichia coli and Klebsiella pneumoniae were 7-10% and 26-31% to the 3rd generation cephalosporin, respectively. The resistance rates to 3rd generation cephalosporin were 22-30% in Citrobacter freundii, 35-44% in Enterobacter cloacae and 15-22 % in Serratia marcescens. Imipenem resistance rates of Pseudomonas aeruginosa and Acinetobacter baumannii were 26% and 17%. Cotrimoxazole and levofloxacin resistance rates of Stenotrophomonas maltophilia were 46% and 44%, respectively.
CONCLUSION
Antimicrobial resistance rates of clinically important pathogens in Korea were still high and were generally higher among the bacteria isolated from the intensive care unit patients. Strict infection control and continuous nationwide surveillance program will be required to manage the antimicrobial resistance problem.
Keyword
MeSH Terms
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Acinetobacter baumannii
Ampicillin
Bacteria*
Citrobacter freundii
Enterobacter cloacae
Enterococcus faecalis
Escherichia coli
Haemophilus influenzae
Hospitals, General
Humans
Imipenem
Infection Control
Intensive Care Units
Klebsiella pneumoniae
Korea*
Levofloxacin
Methicillin-Resistant Staphylococcus aureus
Penicillins
Prevalence
Pseudomonas aeruginosa
Serratia marcescens
Stenotrophomonas maltophilia
Streptococcus pneumoniae
Trimethoprim, Sulfamethoxazole Drug Combination
Ampicillin
Imipenem
Penicillins
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