Kidney Res Clin Pract.
2013 Mar;32(1):43-46.
Association of acute tubular necrosis with gross hematuria in cirrhosis-related immunoglobulin A nephropathy
- Affiliations
-
- 1Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea. nephjo@kuh.ac.kr
- 2Department of Pathology, Konkuk University School of Medicine, Seoul, Korea.
Abstract
- Immunoglobulin A (IgA) nephropathy associated with cirrhosis is the most common form of secondary IgA nephropathy (IgAN). Cirrhosis-related IgAN is usually clinically silent with a rare occurrence of gross hematuria, unlike in cases of idiopathic IgAN. Especially, acute tubular necrosis (ATN) associated with gross hematuria is very rare in cirrhosis-related IgAN, although acute renal failure is a frequently reported complication in advanced cirrhosis. Herein, we report an unusual case of ATN requiring renal replacement therapy, associated with gross hematuria in a patient with nonalcoholic, hepatitis B virus-associated cirrhosis. Results of a histopathological analysis revealed obstruction of the lumen of renal tubules by red blood cell casts, a marked tubular necrosis, and IgA deposition in the mesangium. The patient's renal function and gross hematuria were clearly improved after lamivudine treatment.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- A Case of IgA Nephropathy Associated with Anemia Induced by Persistent Gross Hematuria
- A Case of D-Penicillamine Induced Iga Nephropathy in a Patients with Scleroderma
- Two Cases of Acute Poststreptococcal Glomerulonephritis Superimposing to IgA Nephropathy
- Correlation Between Clinical and Pathological Prognositic Factors of IgA Nephropathy in Children
- A Case of Primary Biliary Cirrhosis -Autoimmune Hepatitis Overlap Syndrome associated with IgA Nephropathy
