- Entecavir+tenofovir vs. lamivudine/telbivudine+adefovir in chronic hepatitis B patients with prior suboptimal response
-
Woo HY, Park JY, Bae SH, Kim CW, Jang JY, Tak WY, Kim DJ, Kim IH, Heo J, Ahn SH
- KMID: 2504510
- Clin Mol Hepatol.
- 2020 Jul;26(3):352-363.
- doi: 10.3350/cmh.2019.0044n
Background/Aims: Suboptimal responses to lamivudine or telbivudine plus adefovir (LAM/LdT+ADV) rescue therapy are common in patients with LAM-resistant hepatitis B virus (HBV) infections. We compared patients switched to entecavir plus... -
- CITED
-
- Close
- SHARE
-
- Close
- Safety and Effectiveness Analysis of Kivexa® (lamivudine/abacavir sulfate) in Human Immunodeficiency Virus Infected Korean Patients
-
Ann H, Lee YS, Kim YS, Jung SI, Lee SH, Lee CS, Lee JS, Choi WS, Choi YH, Kim SW
- KMID: 2450871
- Infect Chemother.
- 2019 Jun;51(2):150-160.
- doi: 10.3947/ic.2019.51.2.150
BACKGROUND: Lamivudine and abacavir sulfate are widely used nucleoside/tide reverse transcriptase inhibitors (NRTI) backbone agents, which are recommended in major international treatment guidelines. The fixed-dose combination of lamivudine and abacavir... -
- CITED
-
- Close
- SHARE
-
- Close
- Therapeutic Efficacy of Lamivudine in Children and Adolescents with Chronic Hepatitis B
-
Choi Y, Bae KS, Kim KH, Koh DK, Kim JH
- KMID: 2418539
- Pediatr Infect Vaccine.
- 2018 Aug;25(2):72-81.
- doi: 10.14776/piv.2018.25.e2
PURPOSE: This prospective study aimed to investigate the therapeutic efficacy of lamivudine in children with chronic hepatitis B virus (HBV) infection. METHODS: During July 2003 through October 2015, children with chronic... -
- CITED
-
- Close
- SHARE
-
- Close
- A Multicenter Study of the Antiviral Efficacy of Entecavir Monotherapy Compared to Lamivudine Monotherapy in Children with Nucleos(t)ide-naïve Chronic Hepatitis B
-
Lee KJ, Choe BH, Choe JY, Kim JY, Jeong IS, Kim JW, Yang HR, Chang JY, Kim KM, Moon JS, Ko JS
- KMID: 2403318
- J Korean Med Sci.
- 2018 Feb;33(8):e63.
- doi: 10.3346/jkms.2018.33.e63
BACKGROUND: The aim of this study was to compare the long-term efficacy of entecavir (ETV) and lamivudine (LAM) therapy in children with chronic hepatitis B (CHB) who had not received... -
- CITED
-
- Close
- SHARE
-
- Close
- Antiviral Efficacy of Tenofovir Monotherapy in Children with Nucleos(t)ide-naive Chronic Hepatitis B
-
Choe JY, Ko JS, Choe BH, Kim JE, Kang B, Lee KJ, Yang HR
- KMID: 2399406
- J Korean Med Sci.
- 2018 Jan;33(2):e11.
- doi: 10.3346/jkms.2018.33.e11
BACKGROUND: The purpose was to compare the efficacy between tenofovir disoproxil fumarate (TDF) and lamivudine (LMV) in children with nucleos(t)ide-naive chronic hepatitis B (CHB) infection. Patients with CHB were treated... -
- CITED
-
- Close
- SHARE
-
- Close
- Efficacy and safety of entecavir versus lamivudine over 5 years of treatment: A randomized controlled trial in Korean patients with hepatitis B e antigen-negative chronic hepatitis B
-
Lee KS, Kweon YO, Um SH, Kim BH, Lim YS, Paik SW, Heo J, Lee HJ, Kim DJ, Kim TH, Lee YS, Byun KS, Kim D, Lee MS, Yu K, Suh DJ
- KMID: 2406042
- Clin Mol Hepatol.
- 2017 Dec;23(4):331-339.
- doi: 10.3350/cmh.2016.0040
BACKGROUND/AIMS: Long-term data on antiviral therapy in Korean patients with hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB) are limited. This study evaluated the efficacy and safety of entecavir... -
- CITED
-
- Close
- SHARE
-
- Close
- Lamivudine: fading into the mists of time
-
Choi J, Lim YS
- KMID: 2406039
- Clin Mol Hepatol.
- 2017 Dec;23(4):314-315.
- doi: 10.3350/cmh.2017.0110
No abstract available. -
- CITED
-
- Close
- SHARE
-
- Close
- Is it possible to predict the development of an entecavir resistance mutation in patients with chronic hepatitis B in clinical practice?
-
Nam JY, Lee JH
- KMID: 2406038
- Clin Mol Hepatol.
- 2017 Dec;23(4):311-313.
- doi: 10.3350/cmh.2017.0069
No abstract available. -
- CITED
-
- Close
- SHARE
-
- Close
- Efficacy of tenofovir-based rescue therapy for chronic hepatitis B patients with resistance to lamivudine and entecavir
-
Jeon HJ, Jung SW, Park NH, Yang Y, Noh JH, Ahn JS, Kim HR, Lee JH, Shin JW
- KMID: 2400670
- Clin Mol Hepatol.
- 2017 Sep;23(3):230-238.
- doi: 10.3350/cmh.2017.0003
BACKGROUND/AIMS: Tenofovir disoproxil fumarate (TDF) monotherapy for 48 weeks provided a virological response comparable to that of TDF and entecavir (ETV) combination therapy in patients infected with ETV-resistant hepatitis B... -
- CITED
-
- Close
- SHARE
-
- Close
- Management of Antiviral Resistance in Chronic Hepatitis B
-
Lim YS
- KMID: 2412184
- Gut Liver.
- 2017 Mar;11(2):189-195.
- doi: 10.5009/gnl15562
The primary goal of therapy for chronic hepatitis B (CHB) is to prevent liver disease progression. Hepatitis B surface antigen (HBsAg) seroclearance or seroconversion is regarded as an optimal endpoint... -
- CITED
-
- Close
- SHARE
-
- Close
- Switch to tenofovir-based therapy or to continue adefovir-based therapy in CHB patients with suboptimal response to adefovir-based combination?
-
Song BC
- KMID: 2373147
- Clin Mol Hepatol.
- 2016 Dec;22(4):439-442.
- doi: 10.3350/cmh.2016.0108
No abstract available. -
- CITED
-
- Close
- SHARE
-
- Close
- The efficacy of tenofovir-based therapy in patients showing suboptimal response to entecavir-adefovir combination therapy
-
Kim JH, Ahn SH, Ko SY, Choe WH, Kim KH, Kwon SY
- KMID: 2373120
- Clin Mol Hepatol.
- 2016 Jun;22(2):241-249.
- doi: 10.3350/cmh.2015.0053
BACKGROUND/AIMS: Before tenofovir (TDF) become available in South Korea, combination therapy with entecavir (ETV) and adefovir (ADV) was the most potent regimen for chronic hepatitis B (CHB) patients who fail... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparison of tenofovir plus lamivudine versus tenofovir monotherapy in patients with lamivudine-resistant chronic hepatitis B
-
Park CH, Jung SW, Shin JW, Bae MA, Lee YI, Park YT, Chung HS, Park NH
- KMID: 2363033
- Clin Mol Hepatol.
- 2016 Mar;22(1):152-159.
- doi: 10.3350/cmh.2016.22.1.152
BACKGROUND/AIMS: Tenofovir disoproxil fumarate (TDF) exhibits similar antiviral efficacy against treatment-naïve and lamivudine (LAM)-resistant chronic hepatitis B (CHB). However, there are few clinical reports on the antiviral effects of TDF-LAM... -
- CITED
-
- Close
- SHARE
-
- Close
- Entecavir plus tenofovir versus entecavir plus adefovir in chronic hepatitis B patients with a suboptimal response to lamivudine and adefovir combination therapy
-
Park JG, Park SY
- KMID: 2351024
- Clin Mol Hepatol.
- 2015 Sep;21(3):242-248.
- doi: 10.3350/cmh.2015.21.3.242
BACKGROUND/AIMS: We compared the efficacies of entecavir (ETV) plus tenofovir (TDF) and ETV plus adefovir (ADV) in chronic hepatitis B (CHB) patients with genotypic resistance to lamivudine (LAM) who showed... -
- CITED
-
- Close
- SHARE
-
- Close
- Impact of prior lamivudine use on the antiviral efficacy and development of resistance to entecavir in chronic hepatitis B patients
-
Hwang JA, Kim KB, Yang MJ, Lim SG, Hwang JC, Cheong JY, Cho SW, Kim SS
- KMID: 2164363
- Clin Mol Hepatol.
- 2015 Jun;21(2):131-140.
- doi: 10.3350/cmh.2015.21.2.131
BACKGROUND/AIMS: To determine the efficacies of entecavir (ETV) in nucleos(t)ide analogue (NA)-naive chronic hepatitis B (CHB) patients and in those with prior lamivudine (LAM) use who did not develop resistance. METHODS:... -
- CITED
-
- Close
- SHARE
-
- Close
- Tenofovir disoproxil fumarate monotherapy for nucleos(t)ide analogue-naive and nucleos(t)ide analogue-experienced chronic hepatitis B patients
-
Jung SK, Kim KA, Ha SY, Lee HK, Kim YD, Lee BH, Paik WH, Kim JW, Bae WK, Kim NH, Lee JS, Jwa YJ
- KMID: 2155290
- Clin Mol Hepatol.
- 2015 Mar;21(1):41-48.
- doi: 10.3350/cmh.2015.21.1.41
BACKGROUND/AIMS: This study investigated the antiviral effects of tenofovir disoproxil fumarate (TDF) monotherapy in nucleos(t)ide analogue (NA)-naive and NA-experienced chronic hepatitis B (CHB) patients. METHODS: CHB patients treated with TDF monotherapy... -
- CITED
-
- Close
- SHARE
-
- Close
- Long-Term Outcomes and Dynamics of Mutants Associated with Lamivudine-Adefovir Rescue Therapy in Patients with Lamivudine-Resistant Chronic Hepatitis B
-
Kim J, Lee SH, Kim HS, Choi K, Jeong SW, Kim SG, Jang JY, Kim YS, Kim BS
- KMID: 2380789
- Gut Liver.
- 2015 Jan;9(1):103-108.
- doi: 10.5009/gnl14018
BACKGROUND/AIMS: To investigate the association between the baseline profiles and dynamics of hepatitis B virus (HBV) DNA polymerase gene mutations and the long-term virological response of lamivudine (LAM)-adefovir (ADV) combination... -
- CITED
-
- Close
- SHARE
-
- Close
- Hepatitis B surface antigen levels at 6 months after treatment can predict the efficacy of lamivudine-adefovir combination therapy in patients with lamivudine-resistant chronic hepatitis B
-
Kim JH, Moon HW, Ko SY, Choe WH, Kwon SY
- KMID: 2069764
- Clin Mol Hepatol.
- 2014 Sep;20(3):274-282.
- doi: 10.3350/cmh.2014.20.3.274
BACKGROUND/AIMS: Quantitation of hepatitis B surface antigen (HBsAg) is an increasingly popular method to determine the treatment response in chronic hepatitis B (CHB) patients. The clinical value of HBsAg level... -
- CITED
-
- Close
- SHARE
-
- Close
- Long-term outcomes of two rescue therapies in lamivudine-refractory patients with chronic hepatitis B: combined lamivudine and adefovir, and 1-mg entecavir
-
Ze E, Baek EK, Lee JJ, Chung HW, Ahn DG, Cho HJ, Kwon JC, Kim HJ, Lee H
- KMID: 2069763
- Clin Mol Hepatol.
- 2014 Sep;20(3):267-273.
- doi: 10.3350/cmh.2014.20.3.267
BACKGROUND/AIMS: Adefovir (ADV) and lamivudine (LAM) combination therapy (ADV+LAM) has been a useful option for patients with LAM-resistant (LAM-r) chronic hepatitis B (CHB). However, the long-term outcomes of LAM+ADV and... -
- CITED
-
- Close
- SHARE
-
- Close
- Rescue therapy with adefovir in decompensated liver cirrhosis patients with lamivudine-resistant hepatitis B virus
-
Woo HY, Choi JY, Yoon SK, Suh DJ, Paik SW, Han KH, Um SH, Kim BI, Lee HJ, Cho M, Lee CK, Kim DJ, Hwang JS
- KMID: 1788566
- Clin Mol Hepatol.
- 2014 Jun;20(2):168-176.
- doi: 10.3350/cmh.2014.20.2.168
BACKGROUND/AIMS: Adefovir dipivoxil (ADV) is a nucleotide analogue that is effective against lamivudine-resistant hepatitis B virus (HBV). The aim of this study was to determine the long-term clinical outcomes after... -
- CITED
-
- Close
- SHARE
-
- Close
