J Korean Ophthalmol Soc.  2014 Sep;55(9):1372-1375. 10.3341/jkos.2014.55.9.1372.

A Case of Epstein-Barr Virus-Related Dacryoadenitis

• Kim SM
• Yoon JS

• KMID: 2217123
• DOI: http://doi.org/10.3341/jkos.2014.55.9.1372

Abstract

PURPOSE
To report a case of Epstein-Barr virus-related dacryoadenitis.
CASE SUMMARY
A 19-year-old female presented with pain, swelling and redness of both upper eyelids. She experienced rhinorrhea, cough and fever for the previous two weeks. Physical exam showed bilateral cervical lymph node enlargement, and orbital computed tomography (CT) revealed diffuse enlargement and inflammation of both lacrimal glands. Serological testing revealed elevated titers for Epstein-Barr virus nuclear antigen immunoglobulin G (IgG) and Epstein-Barr viral capsid antigens IgG and immunoglobulin M (IgM). Based on these results, clinical diagnosis of Epstein-Barr virus-related acute dacryoadenitis was made. The inflammation subsided after conservative management. Relapse was not observed during the three-month follow-up period.
CONCLUSIONS
Based on acute bilateral lacrimal gland enlargement, systemic symptoms such as fever, rhinorrhea, cough, lymphadenopathy and serologically-positive results for Epstein-Barr virus, Epstein-Barr virus-related acute dacryoadenitis can be clinically diagnosed and treated with conservative therapy.

Keyword

Acute dacryoadenitis; Epstein-Barr virus; Painful eyelid swelling

MeSH Terms

Capsid
Cough
Dacryocystitis*
Diagnosis
Eyelids
Female
Fever
Follow-Up Studies
Herpesvirus 4, Human
Humans
Immunoglobulin G
Immunoglobulin M
Inflammation
Lacrimal Apparatus
Lymph Nodes
Lymphatic Diseases
Orbit
Recurrence
Serologic Tests
Young Adult
Immunoglobulin G
Immunoglobulin M

Figure

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  Figure 1. (A) Erythematous swelling of both the upper eyelids at the first visit. (B) No relapse of dacryoadenitis at 3 months after conservative therapy.

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  Figure 2. (A) Orbital computed tomogram without enhancement shows both lacrimal glands enlargement. (B) Axial view shows preseptal soft tissue swelling.

Reference

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