J Korean Ophthalmol Soc.  2006 Feb;47(2):323-327.

A Case of Chronic Central Serous Chorioretinopathy Associated with Pituitary Adenoma

• Kim KS
• Lee SJ
• Lee WK

Abstract

PURPOSE: We report a case of long-standing bilateral chronic central serous chorioretinopathy associated with pituitary adenoma along with a review of the literature.
METHODS
A 42-year-old female had chronic central serous chorioretinopathy that did not improve for 6 months. To evaluate her endocrine state, we checked her serum cortisol level, and found it to be abnormally high. We then referred the patient to a physician.
RESULTS
The patient was diagnosed with Cushing's syndrome due to pituitary adenoma. The tumor was removed by trans-sphenoidal surgical resection. One month after surgery, her serum cortisol level decreased to normal, her visual acuity improved and her fundus examination showed no abnormal findings.
CONCLUSIONS
We propose that patients with chronic, recurrent central serous chorioretinopathy of unknown origin should undergo evaluation of their serum cortisol levels to determine if surgery is needed to treat a primary endocrine abnormality.

Keyword

Central serous chorioretinopathy; Cortisol; Pituitary adenoma

MeSH Terms

Adult
Central Serous Chorioretinopathy*
Cushing Syndrome
Female
Humans
Hydrocortisone
Pituitary Neoplasms*
Visual Acuity
Hydrocortisone