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Anti‑stress effects of Fameyes in in vitro and in vivo models of stresses

Hong J, Lee T, Kim I, Lee S,  Jeon B, Lee J, Won M, Kim S

Background: Fameyes (a mixture of Clematis mandshurica Rupr. extract (CMRE) and Erigeron annuus (L.) Pers. extract (EAPE)) containing scutellarin and chlorogenic acid as major components has been reported to relieve...
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Associations of Perceived Stress Level, Serum Cortisol Level, and Telomere Length of Community-dwelling Adults in Korea

Kim AY, Kim N

Purpose: To investigate associations of perceived stress level, serum cortisol level, and telomere length of community-dwelling adults in Korea. Methods: Data of a total of 135 community-dwelling adults aged over...
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Mediation effect of cord blood cortisol levels between maternal prepregnancy body mass index and birth weight: a hospital-based cross-sectional study

Selvam N, K J, Mithra P

Background: Changes in maternal weight affect the maternal and fetal hypothalamic-pituitary-adrenal axis, influencing birth weight and contributing to the fetal origin of adult diseases (Barker’s hypothesis). This study primarily focused...
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Clinical and Technical Aspects in Free Cortisol Measurement

Choi MH

Accurate measurement of cortisol is critical in adrenal insufficiency as it reduces the risk associated with misdiagnosis and supports the optimization of stress dose. Comprehensive assays have been developed to...
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Age-Limited Effects of Low-Frequency Transcutaneous Electric Nerve Stimulation on Insomnia: A 4-Week Multi-Center, Randomized Controlled Study

Lee HJ, Hong JK, Choi H, Chung S, Yoon IY

Objective Insomnia disorder is a common condition with considerable harmful effects on health. We investigated the therapeutic efficacy and safety of low-frequency transcutaneous electric nerve stimulation (LF-TENS) as an alternative...
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Association between Dissociative Symptoms and Morning Cortisol Levels in Patients with Post-traumatic Stress Disorder

Lee HS, Min D, Baik SY, Kwon A, Jin MJ, Lee SH

Objective: Patients with post-traumatic stress disorder (PTSD) showed inconsistencies in their cortisol level, an index of the hypothalamic-pituitary-adrenal axis function. This study examined the relationship between dissociation, childhood trauma, and...
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Effect of Childhood Trauma on the Association Between Stress-Related Psychological Factors and Hair Cortisol Level in Young Adults

Kim WJ, Park KM, Park JT, Seo E, Bang M, An SK, Park HY, Lee E

Objective Relationship between hair cortisol concentration (HCC) and stress-related psychological measures are inconclusive, possibly due to overlooked heterogeneity regarding childhood trauma and a lack of comprehensive research on stress-related psychological...
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Association between Alcohol Consumption and Serum Cortisol Levels: a Mendelian Randomization Study

Yang JH, Kweon SS, Lee YH, Choi SW, Ryu SY, Nam HS, Park KS, Kim HY, Shin MH

Background: Several studies have reported conflicting results regarding the relationship between alcohol consumption and cortisol levels. However, the causality between alcohol consumption and cortisol levels has not been evaluated. Methods: This...
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Influences of Autonomic Function, Salivary Cortisol and Physical Activity on Cognitive Functions in Institutionalized Older Adults with Mild Cognitive Impairment: Based on Neurovisceral Integration Model

Suh M

Purpose: This study aimed to investigate objectively measured physical activity (PA) in institutionalized older adults with mild cognitive impairment (MCI) and to elucidate the influence of autonomic nervous function, salivary...
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Prenatal Exposure to High Cortisol Induces ADHD-like Behaviors with Delay in Spatial Cognitive Functions during the Post-weaning Period in Rats

Jeon SC, Kim HJ, Ko EA, Jung SC

High levels of cortisol in blood are frequently observed in patients with major depressive disorders and increased cortisol level induces depressivelike symptoms in animal models. However, it is still unclear...
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A Sensitive and Specific Liquid ChromatographyTandem Mass Spectrometry Assay for Simultaneous Quantification of Salivary Melatonin and Cortisol: Development and Comparison With Immunoassays

Shin S, Oh H, Park HR, Joo EY, Lee SY

Melatonin and cortisol are clinically important for diagnosing sleep and mood disorders. We developed and validated a liquid chromatography-tandem mass spectrometry (LC-MS/ MS) assay for simultaneous measurement of salivary melatonin and...
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Incongruent Expression of Brain-Derived Neurotrophic Factor and Cortisol in Schizophrenia: Results from a Randomized Controlled Trial of Laughter Intervention

Cheng SL, Yang FC, Chu HT, Tsai CK, Ku SC, Tseng YT, Yeh TC, Liang CS

Objective Schizophrenia has been associated with dysfunction of the hypothalamic-pituitary-adrenal axis. Furthermore, alterations in neurotrophic factors might contribute to the pathogenesis of schizophrenia. We aimed to evaluate the effects of a...
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Measurement of Circadian Rhythms in the Research of Psychiatric Disorders

Kim SY, Moon E, Jeong HJ

  • KMID: 2508331
  • J Korean Soc Biol Ther Psychiatry.
  • 2020 Oct;26(3):177-183.
The circadian rhythms have been gradually important in psychiatric field. Several studies have shown that major psychiatric disorders, such as schizophrenia, bipolar disorders, and dementia, were highly associated with the...
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Hair Cortisol as a Marker of Intergenerational Heritage of War? A Study of Veterans and Their Offspring

Castro-Vale I, van Rossum EF, Staufenbiel SM, Severo M, Mota-Cardoso R, Carvalho D

Objective Posttraumatic stress disorder (PTSD) has been associated with lower circulating cortisol levels in specific subgroups, which have also been found in the offspring of people with PTSD. The analysis...
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Comparison of salivary and serum cortisol levels in mechanically ventilated patients and non-critically ill patients

Kim JH, Kim YJ, Lee SM, Lee J

Background: Although the measuring free cortisol is ideal for assessment of hypothalamicpituitary-adrenal function, it is not routinely measured. Salivary cortisol correlates well with the biologically active free cortisol. Therefore, this...
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Cortisol Measurements in Cushing's Syndrome: Immunoassay or Mass Spectrometry?

Casals G, Hanzu FA

Determination of cortisol levels in the urine (24 hours urine free cortisol), saliva (late-night), or serum (total cortisol after dexamethasone suppression) is recommended to screen for Cushing's syndrome (CS). This...
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The Correlation of SKA2 with Cortisol, IL-1β and Anxiety in Pregnant Women with the Risk of Preterm Delivery

Ijabi J, Afrisham R, Moradi-Sardareh H, Roozehdar , Seifi F, Ijabi R

Objective The association between preterm birth (PTB), Spindle and Kinetochore Associated Complex Subunit 2 gene (SKA2), cortisol and anxiety have been shown, but in this study, we aimed to clarify...
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Effects of exercise on hematological and serum biochemical parameters in riding ponies

Ko JJ, Lee YW, Seo JP, Lee KK

The purpose of the present study was to investigate changes in hematological and serum biochemical parameters in ponies exercising 3 times a day. The study included 10 healthy 4- to...
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The Effects of Laughter Therapy for the Relief of Employment-Stress in Korean Student Nurses by Assessing Psychological Stress Salivary Cortisol and Subjective Happiness

Lee JS, Lee SK

Objectives Korean student nurses may be exposed to stress caused by their future employment (employment stress). The aim of this study was to investigate the effects of a Laughter Program on...
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The Interaction of Oxytocin and Social Support, Loneliness, and Cortisol Level in Major Depression

Tsai TY, Tseng HH, Chi MH, Chang HH, Wu CK, Yang YK, Chen PS

OBJECTIVE: Loneliness is a specific risk factor for depressive symptoms and suicidal behavior. The present study examined whether the serum oxytocin level would interact with social support and buffers loneliness...
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