J Korean Ophthalmol Soc.  1992 Nov;33(11):1088-1092.

Electronmicroscopic Study of the Effect of Hexamethonium on Serous Choriretinopathy in Rabbits

• Lee HS
• Lee HK
• Yoo JH

Abstract

Stress has been regrarded as one of the causes of central serous chorioretinopathy. We studied the effect of Hexamethonium (ganglionic blocking agent) on experimentaI serous chorioretinopathy following epinephrine injection in rabbits. In group 1, we injected the 0.1 % epinephrine into the rabbits through IV route for 10 days and in group 2, we addited Hexamethonium subcutaneously prior to injection of the epinephrine same term of gorup 1. We could find slight histological changes in gorup 2 as com paired with group 1, which produced serous chorioretinopathy, under the electronmicroscopic study so we would expect the preventive effect of Hexamethonium on the stress-induced serous chorioretinopathy.

Keyword

Electronmicroscope; Epinephrine; Hexamethonium; Serous chorioretinopathy

MeSH Terms

Central Serous Chorioretinopathy
Epinephrine
Hexamethonium*
Rabbits*
Epinephrine
Hexamethonium