J Korean Pediatr Soc.  2001 Oct;44(10):1112-1118.

Growth and Neurodevelopmental Outcome at 15 Months of Corrected Age in Very Low Birth Weight Infants with Chronic Lung Disease

Affiliations
  • 1Department of Pediatrics, Chonnam University, Medical School, Gwangju, Korea. yychoi@chonnam.ac.kr

Abstract

PURPOSE: This study was performed to compare the growth and neurodevelopmental outcome at 15 months of corrected age in very-low-birth weight infants between chronic lung disease(CLD) group and the control group.
METHODS
Very-low-birth-weight infants who were admitted and survived in the NICU(neonatal intensive care units) of Chonnam Univeristy Hospital from Jan. 1997 to Jan. 2000 were divided into two groups, CLD group(n=55) and the control group(n=130). Physical assessment for body weight, length and head circumference, and neurologic examination were done at postconceptional 40 weeks, and then one to two months of interval until the baby reached 15 months of corrected age. Frequency of readmission and presence or absence of cerebral palsy were also examined. Statistical analysis was done between the two groups by SPSS program.
RESULTS
Infants in the CLD group were lighter birth weight with shorter gestational age, and had more neonatal respiratory morbidity and higher readmission rate than that of the control group. Incidence of head growth below third percentile was significantly higher in CLD group, however when the comparison was done below the tenth percentile, there showed no difference between the two groups. Incidences of motor and language delay, and cerebral palsy were not different between the two groups, but the personal-social delay was higher in the CLD group.
CONCLUSION
Incidences of head circumference below third percentile and of personal-social delay at 15 months of corrected age were significantly higher in CLD group than in the control group. But the incidence of cerebral palsy was not different.

Keyword

Very-low-birth-weight; Chronic lung disease; Growth and neurodevelopment

MeSH Terms

Birth Weight
Body Weight
Cerebral Palsy
Gestational Age
Head
Humans
Incidence
Infant*
Infant, Very Low Birth Weight*
Critical Care
Jeollanam-do
Language Development Disorders
Lung Diseases*
Lung*
Neurologic Examination
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