J Korean Ophthalmol Soc.  2002 May;43(5):905-912.

A Case of Acute Lymphoblastic Leukemia with Orbital Relapse

Affiliations
  • 1Department of Opahthalmology, College of Medicine, Kangdong Sacred Heart Hospital, Hallym University, Korea. feeloph@hanmir.com

Abstract

PURPOSE: Acute lympholastic leukemia is common in children but, rare in adults. Authors experienced a case of acute lympholastic leukemia with orbital relapse in adult, and we report this case with literature review.
METHODS
A fifty-year-old woman complained of left eye pain and proptosis for 7 days. The superio-lateral subconjunctival mass excision and biopsy were performed and evisceration was done. The pathologic findings showed the lymphoblastic leukemia. Immunohistochemistry showed the original precursor T-lineage acute lymphoblastic leukemia.
RESULTS
The mass was enlarged 40 days after surgery with pain, and subsided after radiation therapy. We recommended systemic chemotherapy, but she refused the therapy. She died 6months after surgery with systemic relapse.

Keyword

Acute lymphoblastic leukemia; Orbital relapse

MeSH Terms

Adult
Biopsy
Child
Drug Therapy
Exophthalmos
Eye Pain
Female
Humans
Immunohistochemistry
Leukemia
Orbit*
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
Recurrence*
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