Clin Pediatr Hematol Oncol.
2022 Apr;29(1):30-34. 10.15264/cpho.2022.29.1.30.
Isolated Breast Relapse of Early T-Cell Precursor Acute Lymphoblastic Leukemia after Stem Cell Transplantation: A Pediatric Case and Literature Review
- Affiliations
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- 1Department of Pediatrics, Chonnam National University Hwasun Hospital, Hwasun, Korea
- 2Department of Pediatrics, Chonnam National University Medical School, Gwangju, Korea
- 3Department of Radiology, Chonnam National University Hospital, Gwangju, Korea
- 4Department of Pathology, Chonnam National University Hwasun Hospital, Hwasun, Korea
- KMID: 2529690
- DOI: http://doi.org/10.15264/cpho.2022.29.1.30
Abstract
- Extramedullary relapse in acute lymphoblastic leukemia (ALL) usually occurs in the central nervous system and testes those are known as sanctuary sites. Only a few cases of isolated breast relapse after allogeneic hematopoietic stem cell transplantation (HSCT) have been reported in pediatric ALL, with little known about the optimal treatment and prognosis of such cases. Herein, we report a pediatric case of isolated breast relapse with early T-cell precursor ALL after HSCT. We also describe a literature review of six pediatric cases, including our case.
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