Clin Pediatr Hematol Oncol.  2019 Oct;26(2):91-94. 10.15264/cpho.2019.26.2.91.

A Case of Pediatric Acute Lymphoblastic Leukemia with Trisomy 5 as a Sole Chromosomal Anomaly: A Prognostic Significance

Affiliations
  • 1Department of Pediatrics, Gachon University Gil Medical Center, Incheon, Korea. isjeon@gilhospital.com

Abstract

We present a case of Korean pediatric patient with pre-B cell type acute lymphoblastic leukemia (ALL) with trisomy 5 as a sole cytogenetic anomaly. Here, we compare and describe the present case with previous pediatric case reports and provide a review of the literature. This case report may help elucidate the poor prognostic impact of trisomy 5 as a sole cytogenetic anomaly in pediatric patients with ALL. Additional studies are needed to confirm this hypothesis.

Keyword

Trisomy 5; Acute lymphoblastic leukemia; Prognosis; Pediatrics

MeSH Terms

Cytogenetics
Humans
Pediatrics
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
Precursor Cells, B-Lymphoid
Prognosis
Trisomy*
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