J Korean Soc Echocardiogr.  1998 Jul;6(1):69-75.

A Case of Cardiac Maifestations in Postpartum Woman with Mixed Connective Tissue Disease

• Cho YK
• Kim YL
• Lim SW
• Cha DH

Abstract

Mixed Connective Tissue Disease(MCTD) is an overlap syndrome characterized by a combination of clinical features similar to those of systemic lupus erythematosus(SLE), scleroderma, polymyositis, and rheumatoid arthritis and unusually high titers of circulating antibody to a nuclear ribonucleoprotein antigen. The mean age of presentation is 37 years and 80% of patients are female. Cardiac involvement is less common in adults but may be more frequent in children. Pericarditis is the most common finding,' other findings include mitral valve prolapse, myocarditis and congestive heart failure. We experienced a case of pericarditis and asymmetric LV hypertrophy in a 33-yr-old postpartum woman with mixed connective tissue disease, who admitted to our hospital because of fever, dyspnea and chest discomfort, which was diagnosed by echocardiography and selorogic study. She was treated with oral prednisolone and aspirin and presented symptoms improved and pericardial effusion was disappeared.

Keyword

Mixed connective tissue disease; Anti - RNP antibody; Pericarditis

MeSH Terms

Adult
Arthritis, Rheumatoid
Aspirin
Child
Connective Tissue
Dyspnea
Echocardiography
Female
Fever
Heart Failure
Humans
Hypertrophy
Mitral Valve Prolapse
Mixed Connective Tissue Disease*
Myocarditis
Pericardial Effusion
Pericarditis
Polymyositis
Postpartum Period*
Prednisolone
Ribonucleoproteins
Thorax
Aspirin
Prednisolone
Ribonucleoproteins