Korean Circ J.  1993 Jun;23(3):474-480. 10.4070/kcj.1993.23.3.474.

A case of systemic progressive sclerosis after cosmetic surgery with silicone gel

• Kim W
• Lee KS
• Lee CH
• Ko JK

• KMID: 2229240
• DOI: http://doi.org/10.4070/kcj.1993.23.3.474

Abstract

Human Adjuvant Disease(HAD) is a connective tissue disease occuring after cosmetic surgery with a foreign substance. It was first reported by Miyoshi in 1964. There have been specific connective disorders such as systemic lupus erythematosus, rheumatoid arthritis, progressive systemic sclerosis and mixed connective tissue disease. Scleroderma is the single most commonly reported disease. A 55-year-old woman was seen for evaluation of dypnea. Four years previously, she underwent cosmetic surgery with silicone injected directly into eyelid, forehead, both hand and monspubis. The patient presented the classic feature of systemic sclerosis and pericardial effusion. Following pericardiocentesis, she felt somewhat better and became less dyspneic. Seventeen days later, however, she progressively deteriorated and died in spite of intensive medical therapy and supportive care.

Keyword

Human adjuvant disease; Pericardial effusion

MeSH Terms

Arthritis, Rheumatoid
Connective Tissue Diseases
Eyelids
Female
Forehead
Hand
Humans
Lupus Erythematosus, Systemic
Middle Aged
Mixed Connective Tissue Disease
Pericardial Effusion
Pericardiocentesis
Scleroderma, Diffuse
Scleroderma, Systemic
Sclerosis*
Silicone Gels*
Surgery, Plastic*
Silicone Gels