J Korean Rheum Assoc.  2004 Mar;11(1):66-71.

A Case of Cryptococcal Tenosynovitis in a Patient with Wegener's Granulomatosis

Affiliations
  • 1Division of Allergy and Rheumatology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. byoo@amc.seoul.kr
  • 2Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Abstract

Cryptococcosis, a disseminated illness due to Cryptococcus neoformans in most case, is an opportunistic systemic fungal infection that frequently infects the immunosuppressed host. Although it can cause disease in immunocompetent as well as immunocompromised hosts, the later group, particulary those with cell-mediated immune defects, are the greatest risk for severe disseminated disease. Cryptococcal tenosynovitis is extremely rare, with only 2 cases previously documented in the English literature. In this paper we report a case of cryptococcal tenosynovitis with multiple lung nodules in the setting of cryptococcemia in a patient with Wegener's granulomatosis who has been treated with steroid, oral cyclophosphamide for one year.

Keyword

Cryptococcus neoformans; Tenosynovitis; Wegener's granulomatosis

MeSH Terms

Cryptococcosis
Cryptococcus neoformans
Cyclophosphamide
Humans
Immunocompromised Host
Lung
Tenosynovitis*
Wegener Granulomatosis*
Cyclophosphamide
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