J Korean Rheum Assoc.
2006 Mar;13(1):52-55.
A Case of Pyoderma Gangrenosum Associated with Takayasu's Arteritis Responding to Methotrexate
- Affiliations
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- 1The Rheumatology and Rehabilitation Center, Pohang Saint Mary's Hospital, Pohang, Korea. rheumatis@hanmail.net
- 2Department of Pathology, Pohang Saint Mary's Hospital, Pohang, Korea.
- 3Severance Dermatology Clinic, Daegu, Korea.
- 4Department of Dermatology, Kyungpook National University School of Medicine, Daegu, Korea.
Abstract
- Pyoderma gangrenosum (PG) is a vasculitic process, often associated with systemic diseases, including Takayasu's arteritis (TA), rheumatoid arthritis, and inflammatory bowel disease. Most cases of PG associated with TA have been observed in Japan. However, this association is not commonly observed in North American and European patients. PG is often refractory to therapy, requiring high dosages of glucocorticoids. Here, we describe a case of recalcitrant PG that was associated with TA and successfully treated with methotrexate.
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