Korean J Dermatol.  2024 Jul;62(6):353-357.

A Case of Takayasu Arteritis with Pyoderma Gangrenosum

• Lee J
• Lee GW
• Shin JO
• Roh D
• Kim Y
• Won SH
• Lee J
• Shin K
• Kim H
• Ko H
• Kim MB
• Kim B

Abstract

Pyoderma gangrenosum (PG) is a neutrophilic dermatosis characterized by non-infectious ulceration of the skin. It is associated with various systemic diseases, including Takayasu arteritis (TA), rheumatoid arthritis, and inflammatory bowel disease. Notably, the co-occurrence of PG and TA is more frequent among Asians. Here, we present a rare case of TA associated with PG. A 42-year-old woman presented with recurrent ulcers affecting her legs, trunk, arms, and face, which had been refractory to various treatments for 7 years. Recently, the patient had experienced weakness in her left leg, dizziness, and a fever that had persisted for more than a month. Computed tomography angiography revealed thickening and irregularities in the common carotid arteries, right subclavian artery, and aortic arch. TA was diagnosed, following which treatment was initiated with systemic corticosteroids. It is important to consider TA in patients with PG, particularly in young women.

Keyword

Pyoderma gangrenosum; Takayasu arteritis; Vasculitis