Korean J Dermatol.
1999 Jun;37(6):770-774.
A Case of Takayasu's Arteritis Mainfesting with Cutaneous Polyarteritis Nodosa
Abstract
- Takayasu's arteritis is a chronic, granulomatous, large-vessel arteriopathy of unknown cause. A 45-year-old women developed multiple subcutaneous nodules preceded by fever, chills, weakness and weight loss. There were several developed pyoderma gangrenosum-like ulcerations which resulted from the breakdown of subcutaneous nodules on both forearms. A skin biopsy specimen from a forearm nodule revealed characteristics of polyarteritis nodosa including necrosis of the muscular arteries of the deep dermis and subcutaneous tissues destruction of the elastic lamella, thrombus formation, and an acute and chronic inflammatory cell infiltrates. Seven years later, the diagnosis of Takayasu's arteritis was suggested by the absence of the left radial pulse and confirmed by angiography.
