J Korean Soc Pediatr Nephrol.  2014 Apr;18(1):42-46.

An 8-month-old Male Infant with High Grade Vesicoureteral Reflux who Developed Incomplete Kawasaki disease after Recurrent Pyelonephritis

Affiliations
  • 1Department of Pediatrics, CHA Bundang Medical Center, CHA University, Seongnam, Korea. naesusana@gmail.com

Abstract

Kawasaki disease (KD) is a systemic vasculitis that can affect many organ systems. Renal manifestations include pyuria, hematuria, proteinuria, tubulointerstitial nephritis, acute renal failure, hemolytic uremic syndrome, or renal scarring. Although its precise pathogenesis remains unknown, it is considered an autoimmune disease. In the literature, it has been reported that KD may develop in conjunction with urinary tract infections. However, many of these previous studies did not use imaging methods such as renal sonograms, dimercaptosuccinic acid renal scans, and voiding urethrocystograms. We report a case of an 8-month old male infant with high grade vesicoureteral reflux, who developed incomplete KD after recurrent pyelonephritis. Acute pyelonephritis can be an early manifestation of KD. Such cases require the evaluation of urinary tract anomalies according to the guidelines for the management of urinary tract infections.

Keyword

Kawasaki disease; Pyelonephritis; Urinary tract infection; Vesicoureteral reflux

MeSH Terms

Acute Kidney Injury
Autoimmune Diseases
Cicatrix
Hematuria
Hemolytic-Uremic Syndrome
Humans
Infant*
Male
Mucocutaneous Lymph Node Syndrome*
Nephritis, Interstitial
Proteinuria
Pyelonephritis*
Pyuria
Succimer
Systemic Vasculitis
Urinary Tract
Urinary Tract Infections
Vesico-Ureteral Reflux*
Succimer
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