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Etiological and pathophysiological enigmas of severe coronavirus disease 2019, multisystem inflammatory syndrome in children, and Kawasaki disease

Rhim JW, Kang JH, Lee KY

During the coronavirus disease 2019 (COVID-19) pandemic, a novel multisystem inflammatory syndrome in children (MIS-C) has been reported worldwide since the first cases were reported in Europe in April 2020....
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CT Imaging Findings in Non-Atherosclerotic Coronary Artery Disease

Park J, Park B, Kang EJ, Lee J

Acute coronary syndrome (ACS) is mainly caused by atherosclerotic coronary artery disease (CAD); however, it can also occur in patients with non-atherosclerotic CAD. Conventional coronary angiography only shows the lumen...
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Identification of rare coding variants associated with Kawasaki disease by whole exome sequencing

Kim JJ, Hong YM, Yun SW, Lee KY, Yoon KL, Han MK, Kim GB, Kil HR, Song MS, Lee HD, Ha KS, Jun HO, Choi BO, Oh YM, Yu JJ, Jang GY, Lee JK, The Korean Kawasaki Disease Genetics Consortium

Kawasaki disease (KD) is an acute pediatric vasculitis that affects genetically susceptible infants and children. To identify coding variants that influence susceptibility to KD, we conducted whole exome sequencing of...
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Clinical spectrum and short-term outcomes of multisystem inflammatory syndrome in children in a south Indian hospital

Balagurunathan M, Natarajan T, Karthikeyan J, Palanisamy V

Background: Multisystem inflammatory syndrome in children (MIS-C) is a new hyperinflammatory variant that evolved during the coronavirus disease 2019 pandemic. Although the precise pathophysiology of MIS-C is uncertain, it is...
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Late Coronary Aneurysm Formation after Kawasaki Disease: a Review of Mechanistic and Clinical Aspects

Yalta K, Yalta T, Yetkin E, Ozturk C

In patients with Kawasaki disease (KD), evolution of coronary artery aneurysms (CAAs) generally emerges within the first few weeks after disease onset. However, CAA formation in these patients might occasionally...
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Serum Ferritin as a Diagnostic Biomarker for Kawasaki Disease

Kim SH, Song ES, Yoon S, Eom GH, Kang G, Cho YK

Diagnosis of Kawasaki disease (KD) is occasionally delayed because it is solely based on clinical symptoms. Previous studies have attempted to identify diagnostic biomarkers for KD. Recently, patients with KD...
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Clinical features, diagnosis, and outcomes of multisystem inflammatory syndrome in children associated with coronavirus disease 2019

Kwak JH, Lee SY, Choi JW, the Korean Society of Kawasaki Disease

The novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) infection has been spreading worldwide since December 2019. Hundreds of cases of children and adolescents...
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The Importance of Early Recognition, Timely Management, and the Role of Healthcare Providers in Multisystem Inflammatory Syndrome in Children

Lee JH, Han HS, Lee JK

In April 2020, a pediatric report of an unusual inflammatory illness associated with coronavirus disease 2019 (COVID-19) led to similar cases in Europe and North America, which was referred to...
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Toxic Epidermal Necrolysis complicating Infliximab therapy in Refractory Kawasaki disease

Kwak A, Kim SA, Choi HJ

Severe skin reactions complicating tumor necrosis factor-alpha (TNF-α) antagonist therapy were somewhat reported in adults. We report a case of 24-month-old boy with refractory Kawasaki disease who developed toxic epidermal...
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Orange-brown Chromonychia with Features of Splinter Hemorrhage on Dermoscopic Findings

Kim HY, Kim JH, Lee JH, Suh JH, Lee SK, Kim MS, Lee UH

  • KMID: 2508892
  • Korean J Dermatol.
  • 2020 Nov;58(9):614-616.
Kawasaki disease is an acute inflammatory syndrome affecting middle-sized arteries. It is diagnosed when a fever lasts longer than 5 days, and four out of the five diagnostic criteria are...
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Multisystem Inflammatory Syndrome in Children Related to COVID-19: the First Case in Korea

Kim Hn, Shim JY, Ko JH, Yang A, Shim JW, Kim DS, Jung HL, Kwak JH, Sol IS

Since mid-April 2020, cases of multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease 2019 that mimics Kawasaki disease (KD) have been reported in Europe and North America. However,...
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Clinical Study of Specific Cutaneous Complications after BCG Vaccination

Won SH, Shin K, Kim WI, Yang MY, Lee WK, Kim HS, Kim BS, Kim MB, Ko HC

  • KMID: 2505557
  • Korean J Dermatol.
  • 2020 Aug;58(7):453-458.
Background: Bacille Calmette-Guérin (BCG) vaccination has been widely used to prevent severe infections caused by Mycobacterium tuberculosis. Although BCG vaccination is generally safe, some cutaneous complications may occur. However, cutaneous...
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Deep Neck Inflammation: Probable Kawasaki Disease in Korean Children

Lim S, Lee NY, Han SB, Jeong DC, Kang JH

Objectives. Deep neck infections (DNIs) can cause life-threatening complications, and prompt diagnosis and management are necessary. Kawasaki disease (KD) may be accompanied by deep neck inflammation; making it difficult to...
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History and Future of Treatment for Acute Stage Kawasaki Disease

Ishii M, Ebato T, Kato H

Kawasaki disease is a form of vasculitis, mainly in small and medium arteries of unknown origin, occurring frequently in childhood. It is the leading form of childhood-onset acquired heart disease...
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The association between asthma and Kawasaki disease

Choi BS

Kawasaki disease (KD) is a systemic vasculitis and the most common cause of acquired heart disease among preschool-aged children. Asthma is one of the most common chronic illness of childhood....
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Understanding the importance of cerebrovascular involvement in Kawasaki disease

Yeom JS, Cho JY, Woo HO

Kawasaki disease (KD) is a systemic vasculitis in infants and young children. However, its natural history has not been fully elucidated because the first case was reported in the late...
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Significance of Differential Characteristics in Infantile Kawasaki Disease

Kwak JH, Lee J, Ha KS

BACKGROUND AND OBJECTIVES: Immunological variability in Kawasaki disease (KD) shows age-specific differences; however, specific differences in laboratory values have not been compared between infants and non-infants with KD. We compared...
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Iron deficiency anemia as a predictor of coronary artery abnormalities in Kawasaki disease

Kim S, Eun LY

PURPOSE: Coronary artery abnormalities (CAA) are the most important complications of Kawasaki disease (KD). Iron deficiency anemia (IDA) is a prevalent micronutrient deficiency and its association with KD remains unknown....
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Reality of Kawasaki disease epidemiology

Kim GB

Epidemiologic studies of Kawasaki disease (KD) have shown a new pattern or change of its occurrence suggestive of its pathophysiology or risk factors from the first patient with KD reported...
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Change of coronary artery indices according to coronary dominance pattern in early childhood

Lee YJ, Park KS, Kil HR

PURPOSE: Coronary arterial lesion assessment in children can be difficult, depending on the coronary dominance pattern. Although it is easier to determine coronary dominance with echocardiography in children than in...
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