J Korean Assoc Oral Maxillofac Surg.  2012 Aug;38(4):240-244. 10.5125/jkaoms.2012.38.4.240.

Myofibroblastic sarcoma of the mandible: a case report

• Park KR
• Jang HW
• Won JH
• Kim HS
• Cha IH
• Kim HJ

• KMID: 2189631
• DOI: http://doi.org/10.5125/jkaoms.2012.38.4.240

Abstract

Myofibroblastic sarcoma is a rare tumor that mostly develops in the soft tissues of the head and neck. Within the oral cavity, a tongue lesion is the most common. A myofibroblastic sarcoma tends to recur locally instead of metastasizing. We encountered a myofibroblastic sarcoma of the mandible of a 9-year-old male and performed mass excision and additional marginal alveolectomy. So far, there is neither recurrence nor metastasis. We report this case because of the uncommon location of this tumor type and its surgical approach compared to other forms of sarcomas.

Keyword

Myofibroblastic sarcoma; Mandible; Alveolectomy; Uncommon location

MeSH Terms

Alveolectomy
Child
Head
Humans
Male
Mandible
Mouth
Myofibroblasts
Neck
Neoplasm Metastasis
Recurrence
Sarcoma
Tongue

Figure

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  Fig. 1 Intraoral view of soft tissue mass on the lingual side of the mandible showing granulomatous tissue overgrowth.

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  Fig. 2 Initial panoramic view showing radiolucent lesion on #85, 46 apical area with loss of crypt wall of #45.

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  Fig. 3 Radiographic findings of myofibroblastic sarcoma. A. Computed tomography showing osteolytic lesion in the right mandible with cortical destruction on the lingual side. B, C. Magnetic resonance imaging showing 2.5 cm enhancing mass arising from the right mandible with extra-mandibular extension; no gross invasion in the floor of the mouth, tongue, and right sublingual space, with no pathological lymph nodes.

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  Fig. 4 Resected specimen showing well-encapsulated mass. A. Buccal side view. B. Lower part side view.

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  Fig. 5 Histological findings of myofibroblastic sarcoma. A. Microscopic appearance showing streaming fascicles of spindle-shaped and stellate myofibroblasts exhibiting pleomorphism (H&E staining, ×200). B. Immunohistochemical staining with CD34 (×100).

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  Fig. 6 Post-operative panoramic X-ray (A) and clinical photo (B) after 18 months.

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