Oral Biol Res.  2024 Dec;48(4):129-134. 10.21851/obr.48.04.202412.129.

Biphasic synovial sarcoma of the mandible: a case report

Affiliations
  • 1Clinical Instructor, Department of Dentistry, Gyeongsang National University Changwon Hospital, Changwon, Republic of Korea
  • 2Associate Professor, Department of Pathology, Gyeongsang National University School of Medicine, Jinju, Republic of Korea
  • 3Associate Professor, Department of Dentistry, Institute of Medical Science, Gyeongsang National University School of Medicine, Jinju, Republic of Korea

Abstract

Synovial sarcoma is a rare malignant tumor that occurs in the oral and maxillofacial regions, particularly in the mandible. Herein, we report a rare case of biphasic synovial sarcoma of the mandible in an 82-year-old man. The patient was referred with chronic diffuse painful swelling in the right mandible and underwent local resection of the right mandible. Computed tomography revealed severe destruction of the mandible. An initial biopsy revealed osteomyelitis of the jaw. However, immunohistochemical staining and genetic analysis confirmed synovial sarcoma, and the patient underwent additional resection of the mandible. The histological features are described, and the differential diagnoses are discussed.

Keyword

Differential diagnosis; Mandible; Sarcoma, synovial
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