J Korean Neurosurg Soc.  2015 Oct;58(4):385-388. 10.3340/jkns.2015.58.4.385.

Low Grade Myofibroblastic Sarcoma Occurred in the Scalp

• Han SR
• Yee GT

• KMID: 2114378
• DOI: http://doi.org/10.3340/jkns.2015.58.4.385

Abstract

Low-grade myofibroblastic sarcoma (LGMS) is a rare sarcoma with myofibroblastic differentiation. LGMS has a propensity for local recurrence and is associated with a low risk of metastatic spread. A 26-year-old man presented with a 12-month history of a slow growing palpable hard mass in the right parietal scalp. Enhanced CT scan of head showed a 3x4 cm sized well-defined and heterogeneously enhancing scalp mass. The patient underwent excision of the tumor. The histological and immunohistochemical features were consistent with a LGMS. We performed re-operation for remnant tumor removal after diagnosis. After 14 months of surgery, the patient was well-being state.

Keyword

Myofibroblastic sarcoma; Scalp

MeSH Terms

Adult
Diagnosis
Head
Humans
Myofibroblasts*
Rabeprazole
Recurrence
Sarcoma*
Scalp*
Tomography, X-Ray Computed

Figure

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  Fig. 1 Pre (A) and post (B) enhanced axial brain CT scans show a well-defined and enhancing scalp mass, adjacent to the outer table of right parietal bone.

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  Fig. 2 A : Photomicrograph of the tumor reveals a spindle cell tumor with interspersed collagen bundles. The spindle cells show moderate degree of nuclear pleomorphism (hematoxylin and eosin stain, ×200). B : Tumor cells are strong positive for smooth muscle actin on immunohistochemistry (magnification, ×400).

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  Fig. 3 Ultrathin section shows oval and spindle cells having scant cytoplasm. The tumor cells showing scant organelles except dilated rough endoplasmic reticulum. There are primitive intercellular junctions with cytoplasmic dense bodies.

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  Fig. 4 T1WI axial brain MRI (A) shows iso-signal intensity remnant mass in right parietal scalp. Gadolinium enhancement T1WI axial bran MRI (B) reveals the heterogeneously enhancement remnant mass, which measured 0.3×1 cm (arrow).

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  Fig. 5 After 14 months surgery, follow-up T1WI axial (A) and gadolinium enhanced T1WI (B) brain MRI show no recurrence of scalp mass and operation site is clear.

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