Korean J Otorhinolaryngol-Head Neck Surg.  2021 May;64(5):359-364. 10.3342/kjorl-hns.2020.00339.

A Case of Myofibroblastic Sarcoma Originating in the Buccal Mucosa

• Lee IB
• Kim HS
• Lee J
• Lee SH

• KMID: 2516623
• DOI: http://doi.org/10.3342/kjorl-hns.2020.00339

Abstract

Myofibroblastic sarcoma (MS) is an extremely rare form of head and neck tumor that originates from mesenchymal cells. Myofibroblasts are mesenchymal spindle cells that share the features of fibroblasts and smooth muscle cells. Radiologic examinations such as CT and MRI are useful first-line diagnostic tools for differential diagnosis. Complete surgical excision is recommended for successful treatment. MS can be classified as low, intermediate or high grade considering its histological differentiation and time course. Intermediate and high grade MS are known to be related to local recurrence or distant metastasis. With a review of literature, we report a case of MS arising from the left buccal mucosa in a 56-year-old male who complained of a painless left buccal mass. The patient was successfully treated by margin-free excision and the pathologic findings concluded as intermediate grade without any complication. There was no recurrence observed for two years since the surgery.

Keyword

Fibroblasts; Myoblasts; Myofibroblastic sarcomas; Myofibroblasts; Sarcoma