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Endovascular Treatment for Vascular Injuries of the Extremities

Choi TW, Kwon Y, Kim J, Won JH

Vascular injuries of the extremities are associated with a high mortality rate. Conventionally, open surgery is the treatment of choice for peripheral vascular injuries. However, rapid development of devices and...
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Asymptomatic huge spleen mass

Han S, Kim K, Choi IH, Won JH, Yoon SY

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Human Herpesvirus-8 Positive Multicentric Castleman’s Disease with Complete Response after Rituximab Monotherapy: A Case Report

Kim JY, Yoon SY, Lee MY, Lee N, Won JH, Choi IH, Kim KM, Kim KH

Castleman’s disease is a rare non-neoplastic lymphoproliferative disorder of unknown origin. It is classified into unicentric or multicentric based on its anatomical distribution. Multicentric Castleman’s disease can be subdivided according...
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Blindsided: An Unusual Case of Ocular Ischemic Syndrome and Orthostatic Dizziness Caused by Brachiocephalic Trunk Stenosis

Kim YS, Won JH, Lee SJ

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Novel therapeutic strategies for essential thrombocythemia/polycythemia vera

Yoon SY, Won JH

Myeloproliferative neoplasms (MPNs) are clonal disorders of hematopoietic stem cells; these include polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). MPNs are inflammatory cancers, wherein the malignant clone generates...
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Clinical Experience of Allogeneic Hematopoietic Stem Cell Transplantation in Elderly Patients Aged 60 Years and Older in South Korea

Ji YS, Ahn JS, Yun J, Jang GH, Lim SH, Kim SH, Kim CK, Won JH, Park SK

Purpose: The purpose of this study is to share our outcomes and experiences on allogeneic hematopoietic stem cell transplantation (HSCT) in elderly patients aged 60 years and older with myelodysplastic...
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Bare-Metal Stent in Dysfunctional Hemodialysis Access: An Assessment of Circuit Patency according to Access Type and Stent Location

Lee K, Won JH, Kwon Y, Lee SH, Bang JB, Kim J

Purpose To evaluate the circuit patency after nitinol bare-metal stent (BMS) placement according to the type of access and location of the stent in dysfunctional hemodialysis access. Materials and Methods Between January 2017...
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Thrombin Induced Apoptosis through Calcium-Mediated Activation of Cytosolic Phospholipase A2 in Intestinal Myofibroblasts

Park MJ, Won JH, Kim DK

Thrombin is a serine protease that participates in a variety of biological signaling through protease-activated receptors. Intestinal myofibroblasts play central roles in maintaining intestinal homeostasis. In this study, we found...
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Outcomes in Refractory Diffuse Large B-Cell Lymphoma: Results from Two Prospective Korean Cohorts

Yi JH, Jeong SH, Kim SJ, Yoon DH, Kang HJ, Koh Y, Kim JS, Lee WS, Yang DH, Do YR, Kim MK, Yoo KH, Choi YS, Yun WJ, Park Y, Jo JC, Eom HS, Kwak JY, Shin HJ, Park BB, Yi SY, Kwon JH, Oh SY, Kim HJ, Sohn BS, Won JH, Hong DS, Lee HS, Lee GW, Suh C, Kim WS

Purpose Diffuse large B-cell lymphoma (DLBCL) is the most common hematologic malignancy worldwide. Although substantial improvement has been achieved by the frontline rituximab-based chemoimmunotherapy, up to 40%-50% of patients will...
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Busulfan, Melphalan, and Etoposide (BuME) Showed an Equivalent Effect to Busulfan, Cyclophosphamide, and Etoposide (BuCE) as Conditioning Therapy for Autologous Stem Cell Transplantation in Patients with Relapsed or High-Risk Non-Hodgkin’s Lymphoma: A Multicenter Randomized Phase II Study bythe Consortium for Improving Survival of Lymphoma (CISL)

Kim KH, Lee JH, Lee M, Kim HG, Do YR, Park Y, Oh SY, Shin HJ, Kim WS, Park SK, Kong JH, Park MR, Yang DH, Kwak JY, Kang HJ, Mun YC, Won JH

Purpose High-dose chemotherapy followed by autologous stem cell transplantation (ASCT) is the standard management for relapsed or high-risk non-Hodgkin’s lymphoma (NHL). We reported the busulfan, melphalan, and etoposide (BuME) conditioning...
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A Retrospective Analysis of Bone Marrow Examination Results from a Single Center Institution: In What Situations Is Bone Marrow Examination Helpful?

Lee Yk, Kim MJ, Lee MY, Kim KH, Lee N, Won JH, Yoon SY

Objective: Bone marrow (BM) examinations are performed to evaluate hematological abnormalities. Focusing on patients with cytopenia, we aimed to determine the circumstances under which a BM examination can assist in...
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Effects of Prior Short-term Ischemic Preconditioning on Sitting-Induced Lower Limb Vascular Dysfunction in Healthy Men

Won JH, Jae SY

Purpose: The purpose of the study was to examine whether a 7-day ischemic preconditioning (IPC) intervention would attenuate the prolonged sitting-induced lower limb vascular dysfunction in healthy men. Methods: In a...
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A Novel Therapeutic Effect of a New Variant of CTLA4-Ig with Four Antennas That Are Terminally Capped with Sialic Acid in the CTLA4 Region

Piao Y, Yun SY, Kim HS, Park BK, Ha HC, Fu Z, Jang JM, Back MJ, Shin IC, Won JH, Kim DK

Rheumatoid arthritis (RA) is a multifactorial immune-mediated disease, the pathogenesis of which involves different cell types. T-cell activation plays an important role in RA. Therefore, inhibiting T-cell activation is one...
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Pegfilgrastim Prophylaxis Is Effective in the Prevention of Febrile Neutropenia and Reduces Mortality in Patients Aged ≥ 75 Years with Diffuse Large B-Cell Lymphoma Treated with R-CHOP: A Prospective Cohort Study

Jeong SH, Kim SJ, Yoon DH, Park Y, Kang HJ, Koh Y, Lee GW, Lee WS, Yang DH, Do YR, Kim MK, Yoo KH, Choi YS, Yun HJ, Yi JH, Jo JC, Eom HS, Kwak JY, Shin HJ, Park BB, Hyun SY, Yi SY, Kwon JH, Oh SY, Kim HJ, Sohn BS, Won JH, Kim SH, Lee HS, Suh C, Kim WS

Purpose Febrile neutropenia (FN) can cause suboptimal treatment and treatment-related mortality (TRM) in diffuse large B-cell lymphoma (DLBCL) patients treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP). Materials and methods We...
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Early diagnosis of Gaucher disease in Korean patients with unexplained splenomegaly: a multicenter observational study

Do YR, Choi Y, Heo MH, Kim JS, Yoon Jh, Lee JH, Park JS, Sohn SK, Kim SH, Lim S, Chung JS, Jo DY, Eom HS, Kim H, Jeon SY, Won JH, Lee HJ, Shin JW, Jang JH, Yoon SS

Background Gaucher disease (GD) is an autosomal recessive disorder characterized by excessive accumulation of glucosylceramide in multiple organs. This study was performed to determine the detection rate of GD in a...
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Development of a Questionnaire for the Personalized Health Functional Food

Jeon Y, Won JH, Lee DSU, Hong S, Paek YJ, Cho B, Lee H

Background: This study describes the development of a multi-dimensional questionnaire for the personalized recommendation of health functional foods. Methods: The questionnaire was designed to include two parts: common and detailed. Each...
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Recalcitrant Low Back Pain Diagnosed as Hypophosphatemic Osteomalacia Induced by Antiviral Medication

Chae HJ, Won JH, Lee WK, Kim K

We report a rare case of anti-viral agent induced hypophosphatemic osteomalacia presented with localized and radicular pain. A 51-year-old man, who had been taking adefovir for chronic hepatitis, had experienced...
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Trans-Synaptic Degeneration of Peripheral Motor Axons from Metastatic Brain Tumors: Electrophysiological Findings in Two Cases

Won JH, Chae HJ, Kim K, Hyun SE

Denervation potentials obtained during electromyography (EMG) are usually considered as evidence of axonal degeneration in the peripheral nervous system (PNS). However, they may also appear when only central nervous system...
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Eosinophilia in Patients with End Stage Renal Disease Undergoing Hemodialysis

Kim KH, Chang TI, Yoon SY, Lee MY, Lee N, Won JH, Chang MH

Objective: Eosinophilia in patients on hemodialysis has already been reported. It has been associated with allergy to dialyzers and exaggerated activation of complement during hemodialysis. Its etiology, however, remains unknown....
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Hepatic sinusoidal obstruction syndrome/veno-occlusive disease after hematopoietic cell transplantation: historical and current considerations in Korea

Yoon JH, Choi CW, Won JH

Hepatic sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD) is a rare but severe complication of hematopoietic cell transplantation (HCT) showing high mortality. Multiple risk factors for SOS/VOD were identified, but it is...
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