Korean J Dermatol.
2010 Mar;48(3):206-208.
Cutaneous Angiosarcoma Presenting as an Alopecia Patch
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- 1Department of Dermatology, Chonnam National Uinversity Medical School, Gwangju, Korea. seongkim@chonnam.ac.kr
Abstract
- Angiosarcoma is a highly malignant vascular tumor with an incidence of approximately one per ten million. There are three clinical variants; primary angiosarcoma, which occurs on the head and neck in the elderly; angiosarcoma in areas of chronic lymphedema; and post-irradiation angiosarcoma. Primary angiosarcoma shows variable-sized erythematous to violaceous nodules or plaques that become confluent as the lesion progress. We report a case of primary angiosarcoma of the scalp in a 76-year-old man with focal alopecia. Additional immunohistochemical stains showed perifollicular CD34 dominance, which suggested hair follicle-targeted carcinogenesis.
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