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Distinct Repopulation Activity in Hu-Mice between CBand LPB-CD34 Cells by Enrichment of Transcription Factors

Han AR, Lee JE, Lee MJ, Ko SY, Shin HS, Lee JY, Lee DR

Background and Objectives: Human CD34+hematopoietic stem cells can reconstitute the human hematopoietic system when transplanted into immunocompromised mice after irradiation. Human leukapheresis peripheral blood (LPB)-and cord blood (CB)-derived CD34+ cells...
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Post-resection prognosis of patients with hepatic epithelioid hemangioendothelioma

Na BG, Hwang S, Ahn CS, Kim KH, Moon DB, Ha TY, Song GW, Jung DH, Hong SM, Lee SG

Purpose: Epithelioid hemangioendothelioma (EHE) is a rare borderline vascular tumor. This retrospective, single-center study evaluated the outcomes of hepatic resection (HR) in patients with hepatic EHE. Methods: Over the 10-year period...
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Improving Storage Policy in Korean Public Cord Blood Banks: Comparison of Quality between Long-Term and Short-Term Storage of Cord Blood

Lee MN, Kim KH, Kim BG, Goh RY, Kim JN

Background: The decreased use of cord blood units (CBU) due to improvements in haploidentical transplantation is a financial burden for public cord blood banks. Currently, there is no guidance regarding...
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A Conjunctival Myxoid Stromal Tumor

Kim HK, Jang SK, Choi KU, Lee JS

Purpose: We report a conjunctival myxoid stromal tumor (CMST), which is a rare benign conjunctival mass. Case summary: A 70-year-old man with a history of hypertension and cerebral infarction visited our...
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Identification of MicroRNA Related to the CD34+ Cell Fraction of Cord Blood Stem Cells

Lee JH, Song EY, Kim N, Roh EY, Park HW, Yoon JH, Shin S

BACKGROUND: Cord blood (CB) is a reliable source of hematopoietic stem cells, and its utilization in stem cell transplantation is increasing continuously. The CD34+ cell count is arguably one of...
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Enumeration of CD34-positive Stem Cells Using the ADAMII Image-based Fluorescence Cell Counter

Yu H, Yoo J, Hwang JS, Kim M, Bae KH, Jekarl DW, Oh JH, Lee JY, Han S, Chung C, Kim M, Kim Y

BACKGROUND: It is very important to accurately enumerate CD34-positive (CD34+) cells for successful hematopoietic stem cell transplantation (HSCT). We evaluated the ability of the newly developed image based-immunofluorescence cell counter...
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Solitary Fibrous Tumor of Breast with Anaplastic Areas (Malignant Solitary Fibrous Tumor): A Case Report with Review of Literature

Jung MJ, Alrahwan D, Dubrovsky , Baek D, Ayala AG, Ro JY

Solitary fibrous tumor (SFT) is a rare, soft tissue neoplasm that rarely presents in breast tissue, with only 27 previously reported cases. To our knowledge, only one case of malignant...
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Successful engraftment after infusion of multiple low doses of CD34+ cells from a poorly matched sibling donor in a patient with severe aplastic anemia

Kum CD, Lee MJ, Park JE

The dose of CD34+ cells is known to influence the outcome of allogeneic peripheral blood stem cell (PBSC) and/or T-cell-depleted transplantation. A previous study proposed that 2×10⁶ CD34+ cells/kg is...
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PD-L1 Expression on Circulating CD34+ Hematopoietic Stem Cells Closely Correlated with T-cell Apoptosis in Chronic Hepatitis C Infected Patients

Abdellatif H, Shiha G

BACKGROUND AND OBJECTIVES: Lack of understanding of the interplay between hematopoietic stem cells (HSCs) and the immune system has severely hampered stem cell research. Programmed death-1 (PD-L1) has been reported...
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Myxoid Solitary Fibrous Tumor on the Scalp

Kim JH, Kim DC, Lee R, Shin CH, Han YS, Chung SH, Paik SY

Myxoid solitary fibrous tumor (SFT) is very rare soft tissue neoplasm. It is microscopically composed of spindle cells which is individually separated by delicate band of collagen fibers. And this...
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Surface Coating of Polytetrafluoroethylene with Extracellular Matrix and Anti-CD34 Antibodies Facilitates Endothelialization and Inhibits Platelet Adhesion Under Sheer Stress

Chen L, He H, Wang M, Li X, Yin H

Expanded polytetrafluoroethylene (ePTFE) polymers do not support endothelialization because of nonconductive characteristics towards cellular attachment. Inner surface modification of the grafts can improve endothelialization and increase the long-term patency rate...
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Frequency and Distinct Characteristics of Acute Myeloid Leukemia Lacking HLA-DR and CD34 Expression: Features Intermediate between Typical Acute Myeloid Leukemia and Acute Promyelocytic Leukemia

Lee HY, Cho YU, You E, Jang S, Seo EJ, Park CJ

BACKGROUND: The objective of this study was to investigate the frequency and characteristics of HLA-DR⁻/CD34⁻ acute myeloid leukemia (AML) also known as acute promyelocytic leukemia (APL)-like AML. METHODS: This study included...
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Clinical Applicability of Newly Developed Image-based Cell Counter for Counting CD34+ Cells: Comparison with Flow Cytometric Analysis

Rah WJ, Shin EK, Koh H, Suh JY, Chang M, Nam E, Oh JH, Jung Y, Lee JY, Bong SR, Hong SH, Kim JY, Han S, Hwang JK, Chung C, Lee YH

BACKGROUND: Flow cytometric analysis is the standard method for enumerating CD34+ stem cells in hematopoietic stem cell transplantation. However, it has some limitations such as expensive instrumentation, high reagent costs,...
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Immunohistochemical Expressions of D2-40, CD34, and Factor XIIIa between Dermatofibroma and Dermatofibrosarcoma Protuberance

Choi JH, Kim BS, Kim YW, Kim JG, Shin DH, Choi JS, Bae YK

  • KMID: 2350765
  • Korean J Dermatol.
  • 2016 Aug;54(7):525-531.
BACKGROUND: Dermatofibrosarcoma protuberance (DFSP) must be differentiated from dermatofibroma (DF). However, especially in cases of superficial biopsy and cellular dermatofibroma, this is difficult by using histopathology alone since both are...
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Incidental detection of pancreatic hemangioma mimicking a metastatic tumor of renal cell carcinoma

Kim SH, Kim JY, Choi JY, Choi YD, Kim KS

Adult pancreatic hemangioma is a rare disease. We presented a case of a woman with pancreatic tail mass mimicking a distant metastasis from the kidney. A 68-year-old woman was found...
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Comparative Evaluation for Potential Differentiation of Endothelial Progenitor Cells and Mesenchymal Stem Cells into Endothelial-Like Cells

Sabry D, Noh O, Samir M

Understanding the mechanisms of vascular remodeling could lead to more effective treatments for ischemic conditions. We aimed to compare between the abilities of both human Wharton jelly derived mesenchymal stem...
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Dysembryoplastic Neuroepithelial Tumors

Suh YL

Dysembryoplastic neuroepithelial tumor (DNT) is a benign glioneuronal neoplasm that most commonly occurs in children and young adults and may present with medically intractable, chronic seizures. Radiologically, this tumor is...
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Adverse Prognostic Impact of Bone Marrow Microvessel Density in Multiple Myeloma

Lee N, Lee H, Moon SY, Sohn JY, Hwang SM, Yoon OJ, Youn HS, Eom HS, Kong SY

BACKGROUND: Angiogenesis is important for the proliferation and survival of multiple myeloma (MM) cells. Bone marrow (BM) microvessel density (MVD) is a useful marker of angiogenesis and is determined by...
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Correlation between the Severity of Bone Pain and the Amount of CD34+ Cells after Peripheral Blood Stem Cell Mobilization

Seo JW, Choi JS, Kim YH, Yoon SS, Park S, Han KS

BACKGROUND: Peripheral blood stem cells (PBSCs) are mobilized by granulocyte-colony stimulating factor (G-CSF), which causes several side effects in allogeneic donors. We report on side effects of G-CSF administration and...
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Granulocyte Colony-Stimulating Factor for Amyotrophic Lateral Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Study of Iranian Patients

Amirzagar , Nafissi S, Tafakhori , Modabbernia A, Amirzargar A, Ghaffarpour M, Siroos B, Harirchian MH

BACKGROUND AND PURPOSE: The aim of this study was to determine the efficacy and tolerability of granulocyte colony-stimulating factor (G-CSF) in subjects with amyotrophic lateral sclerosis (ALS). METHODS: Forty subjects with...
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