J Korean Assoc Oral Maxillofac Surg.  2012 Aug;38(4):195-203. 10.5125/jkaoms.2012.38.4.195.

Biophysical therapy and biostimulation in unfavorable bony circumstances: adjunctive therapies for osseointegration

• Kim YD

• KMID: 2189626
• DOI: http://doi.org/10.5125/jkaoms.2012.38.4.195

Abstract

Dental implants using titanium have greatly advanced through the improvement of designs and surface treatments. Nonetheless, the anatomical limits and physiological changes of the patient are still regarded as obstacles in increasing the success rate of implants further, even with the enhancement of implant products. So there have been many efforts to overcome these limits. The intrinsic potential for bone regeneration can be stimulated through adjuvant treatments with the continuous improvement of implant properties, and this can play an important role in achieving optimum osseointegration toward peripheral bone tissue and securing ultimate long-term implant stability in standard surgical procedures. For this purpose, various chemical, biological, or biophysical measures were developed such as bone grafts, materials, pharmacological agents, growth factors, and bone formation proteins. The biophysical stimulation of bone union includes non-invasive and safe methods. In the beginning, it was developed as a method to enhance the healing of fractures, but later evolved into Pulsed Electromagnetic Field, Low-Intensity Pulsed Ultrasound, and Low-Level Laser Therapy. Their beneficial effects were confirmed in many studies. This study sought to examine bone-implant union and its latest trend as well as the biophysical stimulation method to enhance the union. In particular, this study suggested the enhancement of the function of cells and tissues under a disadvantageous bone metabolism environment through such adjunctive stimulation. This study is expected to serve as a treatment guideline for implant-bone union under unfavorable circumstances caused by systemic diseases hampering bone metabolism or the host environment.

Keyword

Lasers; Ultrasonic therapy; Osteoblasts; Biosynthesis; Dental implants

MeSH Terms

Bone and Bones
Bone Regeneration
Dental Implants
Electromagnetic Fields
Humans
Intercellular Signaling Peptides and Proteins
Low-Level Light Therapy
Osseointegration
Osteoblasts
Osteogenesis
Proteins
Titanium
Transplants
Ultrasonic Therapy
Dental Implants
Intercellular Signaling Peptides and Proteins
Proteins
Titanium

Figure

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  Fig. 1 A. Low-level laser machine. B. Intraoral probe62.

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  Fig. 2 The application of low-level laser therapy was chosen to stimulate bone healing during guided bone regeneration around the exposed threads of the previous implant.

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